Anti-PP2A Antibody, B subunit, B56 delta, clone H5D12

PP2A is a heterotrimeric phosphatase, ccomposed of A, B and C subunits. The structural A and catalytic C subunits form the constitutive core of the enzyme, which associates with one of a large number of regulatory B subunits. Three families of B subunits have been identified thus far. The prototypical B (or PR55) family of subunits is encoded by three genes, Balpha, Bbeta and Bgamma . The B′ (or B56) family consists of at least seven splice variantsderived from five genes. RNA′s for the two members of the B′′ family, PR72 and PR130, arise by alternative splicing or use of alternate transcription start sites from the same gene. Primary structures as well as functions of B and B′ subunits are conserved from yeast to mammals.

Human PP2A, B subunit, B56 delta. This monoclonal antibody is the delta isoform for the B56 family of protein phosphatase 2A.

GST fusion protein corresponding to the N-terminus of human PP2A, B subunit, B56 delta

Immunoblotting (1:500 to 1:2000)

Optimal working dilutions must be determined by the end user

Research Category
Signaling

Research Sub Category
Kinases & Phosphatases

This Anti-PP2A Antibody, B subunit, B56 delta, clone H5D12 is validated for use in WB for the detection of PP2A.

Format: Purified

Purified mouse monoclonal IgG1 antibody in PBS with 0.05% NaN3.

Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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