推荐产品
等级
certified reference material
质量水平
形式
liquid
特点
Snap-N-Spike®/Snap-N-Shoot®
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
浓度
1.0 mg/mL in methanol
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
clinical testing
格式
single component solution
储存温度
−20°C
SMILES字符串
CSc1ccc2Sc3ccccc3N(CCC4CCCCN4C)c2c1
InChI
1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3
InChI key
KLBQZWRITKRQQV-UHFFFAOYSA-N
基因信息
human ... DRD2(1813) , DRD3(1814) , DRD4(1815) , HTR2A(3356) , HTR2C(3358)
一般描述
An analytical reference standard applicable for use as starting material in calibrators or controls for thioridazine testing methods by LC-MS/MS or GC-MS. Thioridazine is a treatment for schizophrenia sold under trade names Mellaril, Novoridazine, and Thioril.
应用
- Fluorescence Chemosensor Development: Thioridazine solution has been utilized in the synthesis and application of an aldazine-based fluorescence chemosensor. This innovation allows for the sequential detection of Cu²⁺ and biological thiols in aqueous solutions and living cells, enhancing analytical capabilities in biochemical and medical research (Jia et al., 2016).
- Voltammetric Analysis Enhancement: Research involving thioridazine solution has led to the development of a modified glassy carbon electrode with immobilized cobalt nanoparticles. This advancement facilitates the sensitive voltammetric determination of thioridazine, improving detection methods in pharmaceutical and clinical settings (Shahrokhian et al., 2009).
- Microencapsulation Techniques: Thioridazine has been applied in pioneering work on the microencapsulation of drugs using gold nanoparticles. This technique aims to enhance drug delivery systems by improving the bioavailability and controlled release of antipsychotic medications, offering significant benefits for long-term psychiatric treatment (Lai et al., 2006).
法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
靶器官
Eyes,Central nervous system
WGK
WGK 2
闪点(°F)
49.5 °F
闪点(°C)
9.7 °C
法规信息
危险化学品
Maija Purhonen et al.
Pharmacoepidemiology and drug safety, 21(11), 1227-1231 (2012-09-04)
Thioridazine is a first-generation antipsychotic drug that was withdrawn from the market worldwide in 2005. The outcome of clinically stable schizophrenia patients who used thioridazine before market withdrawal was evaluated. Nationwide registers in Finland were utilized to study thioridazine use
Eduardo Abbate et al.
The Journal of antimicrobial chemotherapy, 67(2), 473-477 (2011-12-03)
Current drug choices to treat extensively drug-resistant (XDR) tuberculosis (TB) are scarce; therefore, information on the safety, tolerability and efficacy of alternative regimens is of utmost importance. The aim of this study was to describe the management, drug adverse effects
It is anticipated that as is usually the case, financial motivation will move TZ from its current status “potential anti-MDR/XDR agent,” to one that will cure MDR and XDR TB. Foreword.
Leonard Amaral
Recent patents on anti-infective drug discovery, 6(2), 76-76 (2011-07-30)
Jørn B Christensen et al.
PloS one, 8(3), e57493-e57493 (2013-03-19)
A long list of chemotherapeutical drugs used in the treatment of the peripheral and the central nervous systems possess anti-microbial activity. Some of these neurotropic compounds are chiral, with the one stereo isomeric form exaggerating reduced neurotropism. This is the
Zarir F Udwadia et al.
Recent patents on anti-infective drug discovery, 6(2), 88-91 (2011-06-03)
New drugs are desperately needed to combat XDR-TB as effective treatment involves at least four drugs to which the patient is sensitive or has never received in the past. Most Indian patients have received almost all second line drugs and
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