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Merck
CN

S-024

HU-210 solution

100 μg/mL in methanol, ampule of 1 mL, (Spice Cannabinoid), certified reference material, Cerilliant®

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关于此项目

经验公式（希尔记法）:
C25H38O3
化学文摘社编号:
112830-95-2
分子量:
386.57
EC 号:
200-659-6
UNSPSC代码:
41116107
NACRES:
NA.24

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等级

certified reference material

质量水平

300

表单

liquid

特点

Snap-N-Spike®/Snap-N-Shoot®

包装

ampule of 1 mL

制造商/商品名称

Cerilliant®

drug control

Narcotic Licence Schedule E (Switzerland)

浓度

100 μg/mL in methanol

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

应用

forensics and toxicology
forensics and toxicology

包装形式

single component solution

储存温度

−20°C

SMILES字符串

CCCCCCC(C)(C)c1cc(O)c2[C@@H]3CC(CO)=CC[C@H]3C(C)(C)Oc2c1

InChI

1S/C25H38O3/c1-6-7-8-9-12-24(2,3)18-14-21(27)23-19-13-17(16-26)10-11-20(19)25(4,5)28-22(23)15-18/h10,14-15,19-20,26-27H,6-9,11-13,16H2,1-5H3/t19-,20-/m1/s1

InChI key

SSQJFGMEZBFMNV-WOJBJXKFSA-N

相关类别

一般描述

HU-210 is a synthetic cannabinoid found in the herbal mixture “Spice.” Illicit use of this Spice cannabinoid includes smoking the herbal product to obtain a psychoactive effect. Structurally similar to (-)-Δ8-THC and 11-Hydroxy-Δ9-THC, HU-210 is considerably more potent than natural THC from cannabis and has an extended duration of action.
In July, 2009, the US Drug Enforcement Agency (DEA) placed HU-210 on its Drugs and Chemicals of Concern list. Since HU-210′s placement on this list, DEA has reported seizures of Spice herbal mixtures in Ohio and Florida. HU-210 is currently listed as a Schedule I controlled substance. In recognition of this regulatory challenge, Cerilliant supplies its certified HU-210 reference standard in a convenient, quantitative, DEA-exempt solution.

法律信息

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

靶器官

Eyes

储存分类代码

3 - Flammable liquids

WGK

WGK 1

闪点(°F)

49.5 °F - closed cup

闪点(°C)

9.7 °C - closed cup

法规信息

监管及禁止进口产品
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Valentina Chiodi et al.
Neurobiology of disease, 45(3), 983-991 (2011-12-31)
Cannabinoid CB1 receptors (CB1Rs) are known to be downregulated in patients and in animal models of Huntington's disease (HD). However, the functional meaning of this reduction, if any, is still unclear. Here, the effects of the cannabinoid receptor agonist WIN
Unyong Kim et al.
Journal of pharmaceutical and biomedical analysis, 64-65, 26-34 (2012-03-13)
(6aR,10aR)-9-(Hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol (HU-210) is a synthetic cannabinoid, with a classical cannabinoid structure similar to Δ(9)-tetrahydrocannabinol (Δ(9)-THC). In this study, the in vitro metabolism of HU-210 was investigated in human liver microsomes to characterize associated phase I metabolites. HU-210 was incubated with
Eun Sook Chung et al.
Brain research, 1451, 110-116 (2012-03-23)
We investigated the effects of synthetic cannabinoids, WIN55,212-2 and HU210, on LPS-injected rat substantia nigra in vivo. Intranigral injection of LPS resulted in a significant loss of nigral dopaminergic (DA) neurons, as determined by Nissl staining and TH immunohistochemistry. LPS-induced
L N Maslov et al.
Eksperimental'naia i klinicheskaia farmakologiia, 75(12), 15-18 (2012-01-01)
It was shown that perfusion of the isolated heart of rat with solution containing the CB1- and CB2-receptor agonist HU-210 at concentrations of 0.1 or 1.0 microM/L for a duration of 10 min at 20 min before global ischemia (45
Adrianne R Wilson-Poe et al.
Pharmacology, biochemistry, and behavior, 103(3), 444-449 (2012-10-16)
Co-administration of opioids and cannabinoids can enhance pain relief even when administered on different days. Repeated systemic administration of morphine has been shown to enhance the antinociceptive effect of tetrahydrocannabinol (THC) administered 12h later, and repeated microinjection of the cannabinoid
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Chromatograms

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