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Merck
CN

R-013

Supelco

利培酮-D4标准液 CRM 溶液

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

经验公式(希尔记法):
C23D4H23FN4O2
分子量:
414.51
EC 号:
UNSPSC代码:
41116107
NACRES:
NA.24

等级

certified reference material

质量水平

形式

liquid

特点

Snap-N-Spike®/Snap-N-Shoot®

包装

ampule of 1 mL

制造商/商品名称

Cerilliant®

浓度

100 μg/mL in methanol

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

应用

clinical testing

格式

single component solution

储存温度

−20°C

SMILES字符串

[2H]C([2H])(N1CCC(CC1)c2noc3cc(F)ccc23)C([2H])([2H])C4=C(C)N=C5CCCCN5C4=O

InChI

1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3/i9D2,13D2

InChI key

RAPZEAPATHNIPO-RIEWMPPISA-N

一般描述

利培酮,以Risperdal®、Ridal或Riscalin进行销售,是一种非典型抗精神病药,用于治疗自闭症儿童的精神分裂症、双相情感障碍和易怒症。这种新的内标适用于许多LC/MS和GC/MS应用,包括法医分析、临床毒理学、尿液药物测试或同位素稀释方法。

应用


  • Efficacy and Safety Profiles of Antipsychotic Drugs as Viewed by Psychiatrists: This comparative analysis of cariprazine and risperiDonein clinical settings provides insights into the effectiveness and tolerability of risperidone, a tricyclic antidepressant, emphasizing its role in psychiatric treatment and drug development strategies (Gvozdeckii et al., 2023).

  • Effect of Antipsychotics and Mood Stabilisers on Metabolism in Bipolar Disorder: A network meta-analysis focusing on the impact of medications like risperiDoneon metabolic profiles, crucial for understanding pharmacokinetic behaviors and optimizing therapeutic outcomes in bipolar disorder treatment (Kong et al., 2024).

  • Antipsychotic Prescribing: National Findings of Children and Adolescents Attending Mental Health Services in Ireland: This study details the prescribing patterns of antipsychotics, including risperidone, contributing to a better understanding of its use in pediatric psychiatric care and aiding in the development of guidelines for safer and more effective use of antipsychotics in young populations (Driscoll and McCarthy, 2024).

  • Antipsychotic Medications and Sleep Problems in Patients with Schizophrenia: Investigates the effects of antipsychotic drugs like risperiDoneon sleep disturbances among schizophrenia patients, supporting research into the comprehensive management of sleep issues associated with psychiatric disorders (Cederlöf et al., 2024).

  • Hepatotoxicity to Risperidone: Discusses potential hepatotoxic effects of risperidone, highlighting the importance of monitoring liver function during treatment with this drug, essential for ensuring patient safety in clinical practices (André et al., 2024).



法律信息

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Risperdal is a registered trademark of Johnson & Johnson
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

警示用语:

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

靶器官

Eyes,Central nervous system

WGK

WGK 2

闪点(°F)

49.5 °F

闪点(°C)

9.7 °C

法规信息

危险化学品

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