推荐产品
等级
certified reference material
质量水平
特点
Snap-N-Spike®/Snap-N-Shoot®
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
浓度
100 μg/mL in methanol ((as free phosphate))
包装形式
single component solution
储存温度
−70°C
相关类别
一般描述
This stable-labeled internal standard is suitable for quantitation of PEth 16:0/18:1 in LC/MS or GC/MS applications. PEth 16:0/18:1, also known as phosphatidylethanol 16:0/18:1, is a sensitive and specific biomarker for alcohol use and abuse. Since the detection window of PEth 16:0/18:1 in blood is longer than that of ethyl glucuronide (EtG) or ethyl sulfate (EtS) in urine, measurement of blood PEth 16:0/18:1 level is routinely performed in clinical toxicology and forensic testing applications such as abstinence monitoring and workplace drug testing. PEth 16:0/18:1 has also been investigated as a biomarker to confirm prenatal alcohol exposure (PAE).
应用
- PEth 16:0/18:1-D5 in clinical biomarker research: A study in the Journal of Chromatography B validated a liquid chromatography tandem mass spectrometry (LC-MS/MS) method for analyzing erythrocyte phosphatidylethanol, including deuterated standards like PEth 16:0/18:1-D5. This method highlights critical considerations for using PEth as a clinical biomarker, particularly in monitoring alcohol consumption. The use of deuterated PEth standard ensures precision in quantifying PEth levels, supporting its role in lipidomics and alcohol abuse biomarker detection (White et al., 2022).
法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
靶器官
Eyes,Central nervous system
储存分类代码
3 - Flammable liquids
WGK
WGK 2
闪点(°F)
49.5 °F
闪点(°C)
9.7 °C
法规信息
危险化学品
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