等级
certified reference material
质量水平
形式
liquid
特点
Snap-N-Spike®/Snap-N-Shoot®
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
浓度
1.0 mg/mL in methanol (as free base)
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
forensics and toxicology
格式
single component solution
储存温度
−20°C
SMILES字符串
Cl.CNC[C@H](O)c1cccc(O)c1
InChI
1S/C9H13NO2.ClH/c1-10-6-9(12)7-3-2-4-8(11)5-7;/h2-5,9-12H,6H2,1H3;1H/t9-;/m0./s1
InChI key
OCYSGIYOVXAGKQ-FVGYRXGTSA-N
基因信息
human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146)
一般描述
Phenylephrine, marketed as Neo-Synephrine®, is the most common over-the-counter (OTC) decongestant in the US. Over the last few years, it has been marketed as a substitute for pseudoephedrine with tighter US government regulation of pseudoephedrine from the Combat Methamphetamine Epidemic Act of 2005.
应用
- Stability-Indicating Assay for Ibuprofen and Phenylephrine hydrochloride: A high-performance liquid chromatography (HPLC) method was developed for the eco-friendly and stability-indicating assay of a binary mixture containing phenylephrine hydrochloride, highlighting its role in pharmaceutical quality control and formulation research (Kelani et al., 2023).
- Visual Attention and Adrenergic Manipulation: The differential effects of dopaminergic and noradrenergic manipulations, including the use of phenylephrine, on attention were studied using the theory of visual attention in rat models, providing insights into the neuropharmacological impacts of adrenergic receptor agonists (Hervig et al., 2023).
- Chemometric Quality Assessment: Comparative UV-spectrophotometric analysis using predictive models for the quality assessment of phenylephrine HCl and paracetamol, which is crucial for ensuring the chiral purity and efficacy of pharmaceutical formulations (Farid et al., 2022).
法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Neo-Synephrine is a registered trademark of Bayer Healthcare LLC
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
相关产品
产品编号
说明
价格
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
靶器官
Eyes,Central nervous system
WGK
WGK 2
闪点(°F)
49.5 °F
闪点(°C)
9.7 °C
法规信息
危险化学品
Blacks have a greater sensitivity to α1-adrenoceptor-mediated venoconstriction compared with whites.
Abiodun Adefurin et al.
Hypertension (Dallas, Tex. : 1979), 61(4), 915-920 (2013-02-13)
Blacks have increased hemodynamic responses to both physiological and pharmacological adrenergic stimulation compared with whites, and this may contribute to the greater prevalence of hypertension in this ethnic group. A small study suggested enhanced α1-adrenoreceptor-mediated arterial vasoconstriction in the forearm
Kyungjin Lee et al.
BMC complementary and alternative medicine, 13, 31-31 (2013-02-16)
Prunus yedoensis Matsum. is used as traditional medicine-'Yaeng-Pi' or 'Hua-Pi'-in Japan and Korea. However, no studies have examined the pharmacological activities of the P. yedoensis bark. Only the antioxidant and antiviral activities of P. yedoensis fruit and the anti-hyperglycaemic effect
J Bautista-Ortega et al.
Poultry science, 92(4), 1062-1072 (2013-03-09)
The effects of supplemental l-arginine (Arg), vitamin E (VE), and vitamin C (VC) on vascular reactivity to phenylephrine (PE) were examined in clinically healthy hypoxemic male broiler chickens. One-day-old chicks were housed in wire cages and randomly allocated to 1
Claire W A Pennekamp et al.
Trials, 14, 43-43 (2013-02-16)
Intraoperative arterial hypotension can lead to severe complications in patients undergoing carotid endarterectomy, in particular if cerebral auto-regulation is impaired. Short-acting agents, such as phenylephrine or ephedrine, commonly used to correct intra-operative hypotension, have different hemodynamic effects. Recently, it was
Stephanie W Watts et al.
Arteriosclerosis, thrombosis, and vascular biology, 33(6), 1320-1328 (2013-04-06)
Obesity and hypertension are comorbid in epidemic proportion, yet their biological connection is largely a mystery. The peptide chemerin is a candidate for connecting fat deposits around the blood vessel (perivascular adipose tissue) to arterial contraction. We presently tested the
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