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Merck
CN

P-045

Pheniramine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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经验公式(希尔记法):
C16H20N2
化学文摘社编号:
分子量:
240.34
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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产品名称

Pheniramine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

InChI

1S/C16H20N2/c1-18(2)13-11-15(14-8-4-3-5-9-14)16-10-6-7-12-17-16/h3-10,12,15H,11,13H2,1-2H3

SMILES string

CN(C)CCC(c1ccccc1)c2ccccn2

InChI key

IJHNSHDBIRRJRN-UHFFFAOYSA-N

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

Quality Level

Gene Information

human ... HRH1(3269)

General description

Pheniramine is an antihistamine with sedative effects used for the treatment of hay fever. This certified solution standard is suitable as starting material for the preparation of calibrators and controls in pheniramine testing by GC/MS or LC-MS/MS. Pheniramine is found in over-the-counter cold medicines and in eye-drops such as Visine brand eye drops.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

存储类别

3 - Flammable liquids

wgk

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

法规信息

危险化学品
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Giuseppina Ioele et al.
Chemical & pharmaceutical bulletin, 59(1), 35-40 (2011-01-08)
A chemometric approach based on the combined use of the principal component analysis (PCA) and artificial neural network (ANN) was developed for the multicomponent determination of caffeine (CAF), mepyramine (MEP), phenylpropanolamine (PPA) and pheniramine (PNA) in their pharmaceutical preparations without
Antihistamines in chronic urticaria: threat or treat?
Omür Aydin et al.
Allergologia et immunopathologia, 39(5), 307-309 (2011-01-07)
Julide Sedef Gocmen et al.
Clinical and investigative medicine. Medecine clinique et experimentale, 32(6), E232-E232 (2009-12-17)
In vitro antibacterial activity of topical and systemic antihistaminic preparations containing different active substrates against the standard strains of two bacteria was evaluated. Four topical and 3 systemic preparations containing pheniramine maleate, chlorophenoxamine hydrochloride, and diphenhydramine hydrochloride were studied. The
Successful rapid rituximab desensitization for hypersensitivity reactions to monoclonal antibodies in a patient with rheumatoid arthritis: a remarkable option.
O Abadoglu et al.
Journal of investigational allergology & clinical immunology, 21(4), 319-321 (2011-07-05)
Wenhua Gao et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 904, 121-127 (2012-08-21)
A rapid and efficient dual preconcentration method of on-line single drop liquid-liquid-liquid microextraction (SD-LLLME) coupled to sweeping micellar electrokinetic chromatography (MEKC) was developed for trace analysis of three antihistamines (mizolastine, chlorpheniramine and pheniramine) in human urine. Three analytes were firstly

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