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等级
certified reference material
质量水平
形式
liquid
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
drug control
Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
浓度
1 mg/mL in methanol
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
forensics and toxicology
格式
single component solution
储存温度
-10 to -25°C
SMILES字符串
CCC1(C(=O)NC(=O)NC1=O)c2ccccc2
InChI
1S/C12H12N2O3/c1-2-12(8-6-4-3-5-7-8)9(15)13-11(17)14-10(12)16/h3-7H,2H2,1H3,(H2,13,14,15,16,17)
InChI key
DDBREPKUVSBGFI-UHFFFAOYSA-N
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一般描述
苯巴比妥是最古老、使用最广泛的巴比妥酸盐。该药物是一种抗惊厥药，被批准用于治疗除失神性发作外的所有类型的癫痫发作。该有证标准溶液适合用作制备GC/MS或LC/MS/MS法检测苯巴比妥的校准品和对照品的起始材料。
应用
- Fabrication of a Surface Molecularly Imprinted Polymer Membrane: Phenobarbital is utilized in the development of molecularly imprinted polymer membranes for the selective separation and extraction of various pharmaceutical compounds, enhancing the precision and efficiency of drug monitoring in clinical settings. This application leverages the specific binding properties of Phenobarbital to improve sample preparation techniques for complex biological matrices (Zhao et al., 2024).
- An Isotope Dilution-Liquid Chromatography-Tandem Mass Spectrometry-Based Reference Measurement Procedure: Phenobarbital′s role in establishing reference measurement procedures underscores its importance in ensuring the accuracy and reliability of drug quantification in clinical laboratories. This application supports the standardization of laboratory measurements, critical for patient care and therapeutic monitoring (Schierscher et al., 2024).
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法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
相关产品
产品编号
说明
价格
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
靶器官
Eyes,Central nervous system
WGK
WGK 2
闪点(°F)
49.5 °F
闪点(°C)
9.7 °C
法规信息
监管及禁止进口产品
Shuzhen Liu et al.
Breast cancer research and treatment, 149(2), 439-448 (2015-01-02)
PAM50-defined breast cancer intrinsic subtypes and risk-of-relapse (ROR) scores are prognostic and predictive of endocrine therapy and some chemotherapy. We investigated the prognostic and predictive effect of PAM50 classifications by chemotherapy type. NCIC CTG MA.21 randomized 2,104 patients to doxorubicin
Patrick Kwan et al.
Epilepsia, 45(9), 1141-1149 (2004-08-27)
Phenobarbital (PB) is the most widely used antiepileptic drug (AED) in the developing world and remains a popular choice in many industrialized countries. Meta-analyses of randomized controlled trials suggest that few differences in efficacy exist between PB and other established
M Lundqvist et al.
Acta paediatrica (Oslo, Norway : 1992), 102(9), 863-867 (2013-06-07)
Treatment of neonatal seizures still relies primarily on phenobarbital, despite an estimated efficacy of less than 50% and concern over neurodegenerative side effects. The objective of this study was to evaluate the efficacy and safety of lidocaine as second-line treatment
L Corcos et al.
Pharmacology & toxicology, 89(3), 113-122 (2001-10-09)
Phenobarbital has long been used as a sedative and antiepileptic drug. The drug is the representative of a myriad of lipophilic molecules able to evoke a pleiotropic response in the liver and also in prokaryotes and flies. A great deal
Susumu Kodama et al.
Drug metabolism reviews, 38(1-2), 75-87 (2006-05-11)
In the early 1960s, phenobarbital (PB) was shown to induce hepatic drug metabolism and the induction was implicated in the molecular mechanism of drug tolerance development. Since then, it has become evident that PB not only induces drug metabolism, but
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