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Merck
CN

O-008

Supelco

羟考酮-D6标准液 CRM 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

经验公式(希尔记法):
C18H15NO4D6
分子量:
321.40
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

certified reference material

质量水平

形式

liquid

特点

Snap-N-Spike®/Snap-N-Shoot®

包装

ampule of 1 mL

制造商/商品名称

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

浓度

1.0 mg/mL in methanol

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

应用

forensics and toxicology

格式

single component solution

储存温度

2-8°C

SMILES字符串

[2H]C([2H])([2H])Oc1ccc2C[C@H]3N(CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O)C([2H])([2H])[2H]

InChI

1S/C18H21NO4/c1-19-8-7-17-14-10-3-4-12(22-2)15(14)23-16(17)11(20)5-6-18(17,21)13(19)9-10/h3-4,13,16,21H,5-9H2,1-2H3/t13-,16+,17+,18-/m1/s1/i1D3,2D3

InChI key

BRUQQQPBMZOVGD-UKHJWGAOSA-N

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一般描述

稳定标记的内标物,适用于通过 LC/MS 或 GC/MS 定量测定尿液、血清或血浆中的羟考酮水平,用于尿液药物检测、临床毒理学、法医学分析或同位素稀释法。羟考酮是一种半合成阿片类镇痛药,以许多商品名销售,包括奥施康定 ® 和 Percocet ®,用于治疗中度至重度疼痛。羟考酮还以“Roxies”、“Blues”和“Perks”等商品名非法销售。

应用


  • Oxycodone-D₆ as an isotopic standard: Oxycodone-D₆ is employed extensively as a high-quality isotopic standard in analytical chemistry, particularly in mass spectrometry. This application is crucial for ensuring accuracy and precision in the quantification of oxycoDonein various biological matrices, enhancing drug monitoring and forensic analyses.

  • Stable isotope-labeled oxycoDonefor pharmacokinetic studies: Researchers use Oxycodone-D₆ to investigate the pharmacokinetics of oxycodone, including its absorption, distribution, metabolism, and excretion. The use of this stable isotope-labeled compound allows for more precise tracking of drug metabolites, contributing significantly to the understanding of drug behavior in the human body.

  • Oxycodone-D₆ in metabolite analysis: The deuterated form of oxycoDoneis critical in metabolite profiling studies. It serves as an internal standard that facilitates the identification and quantification of oxycoDonemetabolites, thereby aiding in the exploration of metabolic pathways and potential drug interactions.

  • Use in analytical standard development for biochemistry research: Oxycodone-D₆ solution is integral to developing robust analytical methods for drug testing and research. Its stability and reliability make it a preferred choice for validating new analytical techniques in biochemistry labs.

  • Investigation of opioid receptor binding assays: This compound is utilized in studies exploring opioid receptor interactions, aiding in the development of targeted therapies for pain management. Oxycodone-D₆ helps in understanding the binding efficiency and pharmacodynamics of opioids at the molecular level.

法律信息

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
OxyContin is a registered trademark of Purdue Pharma L.P.
Percocet is a registered trademark of Endo Pharmaceuticals Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

警示用语:

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

靶器官

Eyes

WGK

WGK 1

闪点(°F)

49.5 °F

闪点(°C)

9.7 °C

法规信息

监管及禁止进口产品

分析证书(COA)

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