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Merck
CN

O-002

Supelco

羟考酮标准液 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

经验公式(希尔记法):
C18H21NO4
CAS号:
分子量:
315.36
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

certified reference material

质量水平

表单

liquid

特点

Snap-N-Spike®/Snap-N-Shoot®

包装

ampule of 1 mL

制造商/商品名称

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

浓度

1.0 mg/mL in methanol

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

应用

forensics and toxicology

包装形式

single component solution

储存温度

2-8°C

SMILES字符串

COc1ccc2C[C@H]3N(C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O

InChI

1S/C18H21NO4/c1-19-8-7-17-14-10-3-4-12(22-2)15(14)23-16(17)11(20)5-6-18(17,21)13(19)9-10/h3-4,13,16,21H,5-9H2,1-2H3/t13-,16+,17+,18-/m1/s1

InChI key

BRUQQQPBMZOVGD-XFKAJCMBSA-N

基因信息

human ... OPRM1(4988)

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一般描述

该认证的加标溶液®适用于从临床毒理学和尿液药物测试到法医分析的羟考酮GC/MS或LC/MS测试的许多应用。羟考酮是一种半合成阿片类镇痛药,以许多商品名出售,包括OxyContin®和Percocet®,用于治疗中度至重度疼痛。羟考酮还以“Roxies”,“Blues”和“Perks”等街头名称非法出售。

应用


  • OxycoDonesolution in pediatric perioperative care: OxycoDonesolution has been investigated for its compatibility with other perioperative medications in pediatric settings using Y-type connectors, contributing to safe and effective pain management protocols in children (Youssef et al., 2024).

  • Analytical testing of oxycodone: OxycoDonesolution is utilized in advanced analytical techniques, such as substrate spray mass spectrometry, for the detection of oxycoDoneand naloxone in saliva, showcasing its application in rapid and sensitive diagnostic settings (Millán-Santiago et al., 2024).

  • Study on opioid receptor agonist in exercise physiology: Research has explored the interaction of opioid receptor agonists, including oxycodone, with other compounds in modulating physiological responses to exercise, indicating its role in complex physiological studies (Anselmi et al., 2024).

  • Pharmacological evaluation for pain management: OxycoDonesolution is employed in multivalent vaccination strategies against opioid exposure, providing insights into the development of therapeutic interventions aimed at opioid-related disorders (Song et al., 2024).

  • Quantitative analysis of analgesics: Utilizing HPLC-DAD and LC-MS/MS methods, oxycoDonesolution is critical in the simultaneous determination of multiple analgesics in postoperative solutions, highlighting its importance in pharmacokinetic research and drug monitoring (Yao et al., 2024).

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法律信息

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
OxyContin is a registered trademark of Purdue Pharma L.P.
Percocet is a registered trademark of Endo Pharmaceuticals Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

警示用语:

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

靶器官

Eyes,Central nervous system

储存分类代码

3 - Flammable liquids

WGK

WGK 2

闪点(°F)

49.5 °F - closed cup

闪点(°C)

9.7 °C - closed cup

法规信息

监管及禁止进口产品

从最新的版本中选择一种:

分析证书(COA)

Lot/Batch Number

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访问文档库

Reply to commentary.
Stephen F Butler
The journal of pain : official journal of the American Pain Society, 14(4), 361-362 (2013-04-04)
Raymond E Glazier et al.
Disability and health journal, 6(2), 107-115 (2013-03-20)
Substance abuse (SA) is a grave and pervasive social problem associated with severe personal and social costs that affect persons with disabilities disproportionally. Most previous research has found SA prevalence to be greater among persons with disabilities than among those
Prescrire international, 22(134), 10-11 (2013-02-02)
At high doses of oxycodone, the fixed-dose combination of oxycodone plus naloxone complicates therapeutic management and will likely have lower analgesic efficacy.
James P Zacny et al.
Experimental and clinical psychopharmacology, 21(2), 103-111 (2013-02-21)
Two prominent and important risk factors for nonmedical use of prescription opioids (NMUPO) identified in epidemiological studies are smoking status and sex (i.e., there is a greater likelihood of NMUPO in smokers and in men, relative to nonsmokers and women).
Oxycodone: actions, metabolism, elimination, and detection.
María Luz Rodríguez
MLO: medical laboratory observer, 45(5), 24-24 (2013-06-15)

商品

Although both biphenyl and phenyl-hexyl phases can resolve these compounds, the former exhibits excellent peak shape and substantially less silanol-derived ion exchange activity.

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