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Merck
CN

N-073

硝甲西泮标准液 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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经验公式（希尔记法）:
C16H13N3O3
化学文摘社编号:
2011-67-8
分子量:
295.29
NACRES:
NA.24
PubChem Substance ID:
329818453
UNSPSC Code:
41116107
MDL number:
MFCD00242916

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InChI

1S/C16H13N3O3/c1-18-14-8-7-12(19(21)22)9-13(14)16(17-10-15(18)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3

SMILES string

CN1C(=O)CN=C(c2ccccc2)c3cc(ccc13)[N+]([O-])=O

InChI key

GWUSZQUVEVMBPI-UHFFFAOYSA-N

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal); Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet, kontrollierte Droge in Deutschland

Quality Level

300

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

相关类别

General description

尼美西泮以苯二氮卓类药物Erimin的形式销售，用于治疗难以入睡或维持睡眠的患者的压力或短期严重失眠。据报道，东南亚国家（包括泰国、马来西亚、新加坡和香港）向阿拉巴马州和北卡罗来纳州等州报告了滥用案例。尽管在美国没有用于治疗，但该药物以减轻使用甲基苯丙胺或其他兴奋剂后的低迷而闻名。

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

存储类别

3 - Flammable liquids

wgk

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

法规信息

监管及禁止进口产品
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K Schölermann et al.
Beitrage zur gerichtlichen Medizin, 48, 657-665 (1990-01-01)
The article describes analytical data for the screening and detection of nimetazepam and its major metabolites. The methods comprise thin-layer chromatography, gas chromatography, UV-spectrophotometry, infrared- and mass spectrometry.
T Yotsuyanagi et al.
Clinical and experimental dermatology, 23(3), 113-115 (1998-12-23)
The case is presented of a 34-year-old woman with rhabdomyolysis due to massive intake of nimetazepam, a benzodiazepine hypnotic. On admission, the patient had numerous blisters all over the body. One of the blisters in the gluteal region developed into
L H Peh et al.
Singapore medical journal, 30(1), 72-73 (1989-02-01)
Nimetazepam (Erimin) is a benzodiazepine which has become a new drug of abuse in Singapore. Three cases presenting with psychiatric complications had been treated as inpatients over a period of one and a half years (1986 to 1987) in Woodbridge
[Reduction of nitrazepam and nimetazepam with enteric bacteria].
M Kuroiwa et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 106(5), 414-419 (1986-05-01)
[A case of acute glutethimide poisoning].
M Yao et al.
Masui. The Japanese journal of anesthesiology, 31(9), 1035-1040 (1982-09-01)
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