N-017
去甲哌替啶标准液 溶液
100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
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关于此项目
经验公式（希尔记法）:
C14H19NO2
化学文摘社编号:
分子量:
233.31
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
200-659-6
MDL number:
InChI key
QKHMFBKXTNQCTM-UHFFFAOYSA-N
InChI
1S/C14H19NO2/c1-2-17-13(16)14(8-10-15-11-9-14)12-6-4-3-5-7-12/h3-7,15H,2,8-11H2,1H3
SMILES string
O=C(OCC)C1(C2=CC=CC=C2)CCNCC1
grade
certified reference material
form
liquid
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
drug control
Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
concentration
100 μg/mL in methanol
technique(s)
gas chromatography (GC): suitable, liquid chromatography (LC): suitable
application(s)
forensics and toxicology
format
single component solution
storage temp.
−20°C
Quality Level
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General description
去甲哌替啶是阿片类镇痛药哌替啶的主要有毒代谢物。 该认证Snap-N-Spike®溶液适用于通过LC-MS/MS、LC/MS 或 GC/MS法进行止痛药处方监测、临床毒理学、尿液药物测试或法医分析。哌替啶是一种具有类似吗啡作用的合成阿片类药物，可用作止痛药。
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes,Central nervous system
存储类别
3 - Flammable liquids
wgk
WGK 2
flash_point_f
49.5 °F - closed cup
flash_point_c
9.7 °C - closed cup
法规信息
监管及禁止进口产品
此项目有
Meperidine in patient-controlled analgesia: a near-fatal mishap.
R J Geller
Anesthesia and analgesia, 76(3), 655-657 (1993-03-01)
J L Plummer et al.
Toxicology, 95(1-3), 37-44 (1995-01-06)
This study investigated behavioural effects of the toxic pethidine metabolite, norpethidine, in rats and its interactions with reserpine, apomorphine and physostigmine. Following intraperitoneal administration, brain concentrations of norpethidine reached a plateau after 20-40 min and remained elevated for 2 h.
Thomas T Simopoulos et al.
Archives of surgery (Chicago, Ill. : 1960), 137(1), 84-88 (2002-01-31)
Intravenous patient-controlled analgesia (IV PCA) meperidine hydrochloride can be used with a reasonable margin of safety. A retrospective review was performed of 355 medical records of patients receiving IV PCA meperidine treatment. Four groups of patients were defined, based on
Recognizing normeperidine toxicity.
Patricia McDermot
Nursing, 33(3), 24-24 (2003-03-21)
M Shen et al.
Fa yi xue za zhi, 15(4), 204-207 (2003-01-23)
Using meperidine abusers as subjects for this study, we detected in hair meperidine and its metabolites normeperidine, N-OCH3-meperidine and N-AC-meperidine. The content of meperidine and normeperidine of 60 abusers were 103 +/- 130 ng/mg and 117 +/- 143 ng/mg respectively.
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