推荐产品
等级
certified reference material
质量水平
形式
liquid
特点
Snap-N-Spike®/Snap-N-Shoot®
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
drug control
Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)
浓度
1.0 mg/mL in methanol (as free base)
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
forensics and toxicology
格式
single component solution
储存温度
2-8°C
SMILES字符串
Cl.COC(=O)C(C1CCCCN1)c2ccccc2
InChI
1S/C14H19NO2.ClH/c1-17-14(16)13(11-7-3-2-4-8-11)12-9-5-6-10-15-12;/h2-4,7-8,12-13,15H,5-6,9-10H2,1H3;1H
InChI key
JUMYIBMBTDDLNG-UHFFFAOYSA-N
基因信息
human ... SLC6A2(6530) , SLC6A3(6531)
一般描述
哌醋甲酯是一种精神刺激药，用于注意力缺陷多动症（ADHD），心动过速和嗜眠症的治疗。该经认证的加标溶液®适用于尿液药物测试、临床毒理学和法医分析的LC/MS或GC/MS应用。哌醋甲酯以商品名Concerta®和Ritalin®出售。
应用
- Methylphenidate HCl solution in ADHD pharmacotherapy studies: Research published in "Molecular Psychiatry" explored the effects of methylphenidate on Drosophila brain at single-cell resolution, highlighting its potential for ADHD treatment repurposing and its impact on neurotransmitter regulation (Qu et al., 2023).
- CNS stimulant research with high-purity methylphenidate HCl: A case study in "Children (Basel)" detailed the complex relationship between ADHD symptoms and self-induced weight loss in a child, underscoring methylphenidate′s role in managing hyperkinetic disorders and its potential interactions with eating behaviors (Mestermann et al., 2023).
- Neuropharmacology Methylphenidate in neurotransmitter research: A review in "Molecular Biotechnology" discussed the pharmacological applications of amino acids, using methodologies that could be applied to substances like methylphenidate for enhanced understanding of its interaction with brain chemistry and neurotransmitter functions (Kamaraj and Vuppu, 2023).
- Liquid methylphenidate for in vitro neuropharmacology studies: An analysis in "Journal of Medical Internet Research" investigated the nonmedical use and adverse effects of methylphenidate, providing insights into its impact during the COVID-19 pandemic and highlighting the importance of monitoring drug usage trends for improved public health strategies (Shin et al., 2023).
- Dopamine reuptake inhibitor research with methylphenidate solution: A report in "Journal of Analytical Toxicology" detailed a case of fatal intoxication where methylphenidate′s properties as a dopamine reuptake inhibitor were considered in the context of its toxicological profile, emphasizing the need for careful monitoring of its use and effects (Ameline et al., 2023).
法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Concerta is a registered trademark of ALZA Corporation
Ritalin is a registered trademark of Novartis Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
相关产品
产品编号
说明
价格
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
靶器官
Eyes,Central nervous system
WGK
WGK 2
闪点(°F)
closed cup
闪点(°C)
closed cup
法规信息
监管及禁止进口产品
Evert J Semeijn et al.
Journal of the American Geriatrics Society, 61(6), 882-887 (2013-05-29)
To increase insight into the effect of attention-deficit/hyperactivity disorder (ADHD) on health in general in older adults. Two-phase sampling side-study. Longitudinal Aging Study Amsterdam (LASA). Two hundred twenty-three randomly selected LASA respondents. Information was collected during home visits on physical
Methylphenidate in the management of cancer-related fatigue.
Patrick C Stone
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(19), 2372-2373 (2013-05-22)
Eduardo Bruera et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(19), 2421-2427 (2013-05-22)
Cancer-related-fatigue (CRF) is common in advanced cancer. The primary objective of the study was to compare the effects of methylphenidate (MP) with those of placebo (PL) on CRF as measured using the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) fatigue
Sucharita S Somkuwar et al.
Biochemical pharmacology, 86(2), 309-316 (2013-04-30)
Attention deficit/hyperactivity disorder (ADHD) is attributed to dysfunction of the prefrontal cortex. Methylphenidate, an inhibitor of dopamine and norepinephrine transporters (DAT and NET, respectively), is a standard treatment for ADHD. The Spontaneously Hypertensive Rat (SHR) is a well-established animal model
Liv Larsen Stray et al.
Behavioral and brain functions : BBF, 9, 18-18 (2013-05-07)
Most children who are diagnosed with attention deficit-hyperactivity disorder (ADHD) have moderate-to-severe motor problems using the Motor Function Neurological Assessment battery (MFNU). The MFNU focuses on specific muscle adjustment problems associated with ADHD, especially motor inhibition problems and high muscle
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