推荐产品
等级
certified reference material
质量水平
形式
liquid
特点
Snap-N-Spike®/Snap-N-Shoot®
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
浓度
1.0 mg/mL in acetonitrile
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
clinical testing
格式
single component solution
储存温度
−20°C
SMILES字符串
[2H][13C]([2H])([2H])OC[C@@H](NC(C)=O)C(=O)NCc1ccccc1
InChI
1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3,(H,14,17)(H,15,16)/t12-/m1/s1/i2+1D3
InChI key
VPPJLAIAVCUEMN-RUXIMPAMSA-N
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一般描述
An internal standard suitable for GC/MS or LC/MS applications in lacosamide testing from clinical toxicology and forensic analysis to urine drug testing and isotope dilution methods. Lacosamide is a new antiepileptic drug approved by the FDA in late 2008 for the treatment of partial-onset seizures and diabetic neuropathic pain. The drug is marketed under the trade name Vimpat®.
应用
- Pharmacokinetic study of lacosamide: A study employed ultra-performance liquid chromatography coupled with tandem mass spectrometry (UPLC-MS/MS) to selectively quantify lacosamide in human plasma. Lacosamide-¹³C, D₃ was utilized as an internal standard to facilitate precise measurement during pharmacokinetic evaluations in healthy subjects, enhancing the understanding of dose-dependent dynamics (Bharwad et al., 2020).
法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Vimpat is a registered trademark of Harris FRC Corporation
警示用语：
Danger
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
WGK
WGK 2
闪点(°F)
35.6 °F
闪点(°C)
2 °C
法规信息
危险化学品
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