等级
certified reference material
质量水平
形式
liquid
特点
Snap-N-Spike®/Snap-N-Shoot®
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
浓度
1.0 mg/mL in methanol
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
clinical testing
格式
single component solution
储存温度
−20°C
一般描述
Hydroxylurasidone is the most abundant metabolite of lurasidone in urine. Lurasidone, marketed under the trade name Latuda®, is a new atypical antipsychotic developed for the treatment of schizophrenia and episodes of depression in adults with bipolar disorder (manic depression). A certified solution standard suitable for use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, pharmaceutical research, or urine drug testing.
法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Latuda is a registered trademark of Dainippon Sumitomo Pharma Co., Ltd.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
靶器官
Eyes
WGK
WGK 2
闪点(°F)
closed cup
闪点(°C)
closed cup
法规信息
危险化学品
Eleonora Lapi et al.
Molecular cell, 32(6), 803-814 (2008-12-30)
p73 has been identified as a structural and functional homolog of the tumor suppressor p53. The transcriptional coactivator Yes-associated protein (YAP) has been demonstrated to interact with and to enhance p73-dependent apoptosis in response to DNA damage. Here, we show
Christina J Matheny et al.
Chemistry & biology, 20(11), 1352-1363 (2013-11-05)
Phenotypic high-throughput chemical screens allow for discovery of small molecules that modulate complex phenotypes and provide lead compounds for novel therapies; however, identification of the mechanistically relevant targets remains a major experimental challenge. We report the application of sequential unbiased
Kenneth D Harrison et al.
The EMBO journal, 30(12), 2490-2500 (2011-05-17)
Dolichol monophosphate (Dol-P) functions as an obligate glycosyl carrier lipid in protein glycosylation reactions. Dol-P is synthesized by the successive condensation of isopentenyl diphosphate (IPP), with farnesyl diphosphate catalysed by a cis-isoprenyltransferase (cis-IPTase) activity. Despite the recognition of cis-IPTase activity
Peng Wang et al.
Nature medicine, 21(4), 383-388 (2015-03-10)
Types 1 and 2 diabetes affect some 380 million people worldwide. Both ultimately result from a deficiency of functional pancreatic insulin-producing beta cells. Beta cells proliferate in humans during a brief temporal window beginning around the time of birth, with
Justin H Hwang et al.
Journal of virology, 88(20), 12055-12064 (2014-08-15)
Murine polyomavirus small t antigen (PyST) regulates cell cycle, cell survival, apoptosis, and differentiation and cooperates with middle T antigen (MT) to transform primary cells in vitro and in vivo. Like all polyomavirus T antigens, PyST functions largely via its
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