等级
certified reference material
质量水平
形式
liquid
特点
Snap-N-Spike®/Snap-N-Shoot®
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
浓度
100 μg/mL in methanol with 0.1N NH3
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
forensics and toxicology
格式
single component solution
储存温度
−70°C
SMILES字符串
CC[C@@H]1CN2CC[C@@]3(O)C(=Nc4cccc(OC)c34)[C@@H]2C[C@@H]1\C(=C/OC)C(=O)OC
InChI
1S/C23H30N2O5/c1-5-14-12-25-10-9-23(27)20-17(7-6-8-19(20)29-3)24-21(23)18(25)11-15(14)16(13-28-2)22(26)30-4/h6-8,13-15,18,27H,5,9-12H2,1-4H3/b16-13+/t14-,15+,18+,23+/m1/s1
InChI key
RYENLSMHLCNXJT-CYXFISRXSA-N
一般描述
Along with mitragynine, 7-Hydroxymitragynine is an active alkaloid found in the plant Mitragynine speciosa, commonly known as Kratom. The compound possesses opioid agonistic activity with a potentcy 30- and 17-fold higher than that of mitragynine and morphine, respectively.
应用
- 7-Hydroxymitragynine research solution for opioid receptor studies: The solution is utilized extensively in opioid receptor agonist research, providing insights into its binding efficacy and downstream effects in neurochemical pathways. This research contributes to understanding opioid-like effects and potential therapeutic uses for pain management and addiction treatment (Zhang et al., 2022).
- Kratom alkaloid standard in bioactive studies: As a bioactive mitragynine derivative, 7-Hydroxymitragynine is employed as a standard in the study of various kratom alkaloids, which aids in elucidating their pharmacological profiles and potential medicinal benefits. This is crucial for developing safe and effective kratom-based treatments (Henningfield et al., 2021).
- Analgesic compound research in pain management: Research on 7-Hydroxymitragynine focuses on its analgesic properties, exploring its effectiveness and safety as a pain-relieving compound. This research is vital for proposing alternatives to traditional opioids, offering potential benefits in terms of reduced side effects and lower addiction risks (Chakraborty et al., 2021).
- High-purity standard for synthetic studies: The high-purity 7-Hydroxymitragynine solution is critical for synthetic and biochemical assays, allowing researchers to study its effects on a molecular level in vitro. This facilitates a deeper understanding of its interaction with biological systems, aiding in the design of targeted pharmacotherapies (Bhowmik et al., 2021).
- Research-grade compound in neurochemistry: Used in neurochemistry to study the effects of kratom extracts and their derivatives, 7-Hydroxymitragynine solution helps delineate its role in altering neurotransmitter release. This research supports the development of novel therapies for disorders characterized by neurotransmitter dysregulation (Zhang et al., 2020).
法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
靶器官
Eyes
WGK
WGK 2
闪点(°F)
35.6 °F
闪点(°C)
2 °C
法规信息
监管及禁止进口产品
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