推荐产品
等级
certified reference material
质量水平
表单
liquid
特点
Snap-N-Spike®/Snap-N-Shoot®
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
drug control
Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)
浓度
1.0 mg/mL in methanol (as salt)
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
forensics and toxicology
包装形式
single component solution
储存温度
−20°C
SMILES字符串
OCCCC([O-])=O.[Na+]
InChI
1S/C4H8O3/c5-3-1-2-4(6)7/h5H,1-3H2,(H,6,7)/p-1
InChI key
SJZRECIVHVDYJC-UHFFFAOYSA-M
一般描述
GHB，或γ-羟基丁酸酯，是一种以Xyrem®品牌名出售的中枢神经系统抑制剂，并可医用于治疗发作性睡病、白天过度嗜睡以及极少数情况下的酗酒。GHB还被娱乐性地用作麻醉剂和约会强奸药。它众多的俗称包括“GBH”、“X液体”、“G”、“果汁”和“密耳”。
应用
- 睡眠障碍研究中的GHB钠盐：一项关于夜用羟丁酸钠（GHB钠盐的一种形式）的研究表明，觉醒时前扣带皮层的磁共振谷氨酸信号增强，这说明羟丁酸钠在睡眠研究中有调节大脑功能的潜在应用（Dornbierer et al., 2023）。
- GHB-Na+在酒精成瘾治疗中的研究：研究侧重于γ-羟基丁酸钠盐（GHB）治疗酒精成瘾的功效，它能让人有效地维持禁欲，减少对酒精的渴望，降低复发率（Frisoni et al., 2023）。
- 用于体外生化测定的γ-羟基丁酸钠：研究人员对受酒精干扰的大鼠体内γ-羟基丁酸酯（GHB）的药代动力学和代谢进行了详细研究，该研究为GHB生化行为和与酒精的相互作用的体外研究提供了一个模板（Kim et al., 2023）。
法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Xyrem is a registered trademark of JPI Commercial, LLC
相关产品
产品编号
说明
价格
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
靶器官
Eyes
储存分类代码
3 - Flammable liquids
WGK
WGK 1
闪点(°F)
49.5 °F - closed cup
闪点(°C)
9.7 °C - closed cup
法规信息
监管及禁止进口产品
Franklyn H Geary et al.
Clinical obstetrics and gynecology, 56(1), 166-172 (2013-02-02)
The drug abusing patient can provide a management dilemma for health care providers including nurses, obstetrician, anesthesiologist, and pediatrician. Certain illicit drugs may mimic other diseases of pregnancy and result in inappropriate treatment for the mother and child. Pain management
Shilpa R Kauta et al.
Pediatric neurology, 47(5), 362-365 (2012-10-10)
Narcolepsy is characterized by recurrent brief attacks of irresistible sleepiness. Signs can begin during childhood. However, diagnoses are frequently delayed by 10-15 years because of unfamiliarity with pediatric narcolepsy and variable presentations of its associated features (cataplexy, hypnagogic/hypnopompic hallucinations, and
Maria Maj Jensen et al.
Ugeskrift for laeger, 174(25), 1749-1750 (2012-06-21)
Gammahydroxybutyrate (GHB) is also known as fantasy or liquid ecstasy. Its use as a recreational drug has been illegal in Denmark since 1999. However, the GHB pro-drug gammabutyrolactone (GBL) is available to everybody since it is the main ingredient in
Elisabetta Bertol et al.
Journal of pharmaceutical and biomedical analysis, 70, 518-522 (2012-08-14)
A gas chromatography-mass spectrometry (GC-MS) and a liquid chromatography tandem mass spectrometry (LC-MS/MS) method were validated for quantifying endogenous and exogenous hair concentrations of gamma-hydroxybutyrate (GHB). The GC-MS method is based on overnight extraction of 25 mg hair in NaOH
Jae Seong Lee et al.
Journal of biotechnology, 161(1), 34-41 (2012-06-26)
Previous research showed that co-down-regulation of caspase-3/7 in rCHO cells, unlike Bcl-2 overexpression, did not effectively block apoptotic cell death induced by 3mM sodium butyrate (NaBu). Here, it is found that the control of autophagy is also related to this
相关内容
默克Supelco®标准物质不断推出或更新满足海关及法规要求的标准物质。每年我们约有上百种的新CRM或标准物质上市，在此我们尽可能多的列出满足海关及法规要求的标准物质。
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门