等级
certified reference material
质量水平
形式
liquid
特点
Snap-N-Spike®/Snap-N-Shoot®
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
drug control
Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
浓度
100 μg/mL in methanol
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
forensics and toxicology
格式
single component solution
储存温度
2-8°C
SMILES字符串
CCC(=O)N(C1CCN(CC1)CCc2ccccc2)c3ccccc3
InChI
1S/C22H28N2O/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19/h3-12,21H,2,13-18H2,1H3
InChI key
PJMPHNIQZUBGLI-UHFFFAOYSA-N
基因信息
human ... OPRM1(4988)
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一般描述
一种有效的合成麻醉性止痛药和局麻药，起效快，作用时间短。芬太尼以 Duragesic®、Actiq®和Fentora® 等各种商品名出售，在镇痛活性方面比吗啡更有效。该认证的溶液标准适用于各种LC/MS或GC/MS测试应用，包括从法医分析、临床毒理学和止痛处方监测到尿液药物测试和药物研究。
应用
- Analgesic potency assay: Fentanyl is widely used in analgesic potency assays due to its strong opioid receptor agonist properties, providing a benchmark for evaluating the efficacy of new analgesics in preclinical and clinical settings (Chakravartula et al., 2024).
- In vitro pharmacology studies: As a high-purity fentanyl analytical standard, it is crucial for in vitro pharmacology studies to understand the drug′s interaction with opioid receptors and its effects on neural pathways (Kanashiro et al., 2024).
- Pharmacological research chemical supply: Fentanyl citrate solution serves as a valuable resource in pharmacological research, particularly in studies focusing on pain management and opioid addiction therapies (Lee et al., 2024).
- Synthetic opioid solution: This synthetic opioid is utilized in scientific studies to explore safer and more effective pain relief methods, such as patient-controlled analgesia systems (Huang et al., 2024).
- Opioid receptor agonist research: Fentanyl is employed to study opioid receptor dynamics, aiding in the development of targeted therapies for pain and opioid use disorders (Song et al., 2024).
法律信息
Actiq is a registered trademark of Anesta Corp.
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Duragesic is a registered trademark of Johnson & Johnson
Fentora is a registered trademark of Cima Labs, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
相关产品
产品编号
说明
价格
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
靶器官
Eyes,Central nervous system
WGK
WGK 2
闪点(°F)
49.5 °F
闪点(°C)
9.7 °C
法规信息
监管及禁止进口产品
[Pain therapy. Treating pain patients with opioid preparations].
MMW Fortschritte der Medizin, 155(6), 70-71 (2013-05-25)
An EMS guide to chronic pain.
Kevin T Collopy et al.
EMS world, 42(7), 59-63 (2013-08-10)
Nele Plock et al.
International journal of clinical pharmacology and therapeutics, 51(6), 495-508 (2013-04-25)
Intranasal Fentanyl Spray (INFS) was developed for the treatment of breakthrough pain (BTP) in cancer patients using a new route of administration. Dose strengths of 50, 100, and 200 μg INFS (Instanyl®) are currently on the market, however, some adult
Terry J Kreeger et al.
Journal of wildlife diseases, 49(3), 674-678 (2013-06-20)
Seven grizzly (Ursus arctos; four male, three female) and three black (Ursus americanus; two male, one female) bears caught in culvert traps or leg snares were immobilized in northwestern Wyoming with carfentanil and xylazine at doses, respectively, of 0.011 ±
Elzbieta P Wala et al.
Journal of opioid management, 9(2), 85-96 (2013-05-28)
Opioids may cause progressive enhancement of pain sensitivity (opioid-induced hyperalgesia [OIH]) and thus, exacerbate existing pain. Animal studies also demonstrate paradoxical OIH with an ultralow dose (ULD, subanalgesic) of opioid; eg, the μ-opioid, morphine. Repeated administration of ULD-morphine resulted in
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