InChI
1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,17+,18+/m1/s1
SMILES string
CC12CCC3C(CCc4cc(O)ccc34)C1CC(O)C2O
InChI key
PROQIPRRNZUXQM-ZXXIGWHRSA-N
grade
certified reference material
Quality Level
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
1.0 mg/mL in methanol
technique(s)
gas chromatography (GC): suitable, liquid chromatography (LC): suitable
format
single component solution
storage temp.
−20°C
General description
雌三醇是雌二醇的代谢产物,是尿液中发现的主要雌激素。妊娠期间,通过LC-MS/MS测量血清,血浆或尿液中的雌三醇水平,作为母亲筛查唐氏综合症胎儿的一部分。
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes,Central nervous system
存储类别
3 - Flammable liquids
wgk
WGK 2
flash_point_f
49.5 °F - closed cup
flash_point_c
9.7 °C - closed cup
法规信息
危险化学品
此项目有
Swastika Surujlal-Naicker et al.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 48(1), 37-47 (2012-10-04)
Wastewater effluents have been documented as major contributors of hormone endocrine disrupting compounds (EDCs) in to the aquatic ecosystem. The need for rapid, simple and cost effective methods to detect these EDCs has increased. The use of Radio-immunoassays (RIA) were
Mitsuhiro Ueda et al.
Enzyme and microbial technology, 51(6-7), 402-407 (2012-10-09)
A protein with strong removal activity against the natural estrogen estriol was purified from a culture supernatant of Pleurotus eryngii var. tuoliensis C.J. Mou. The protein was characterized as a laccase and had a molecular mass of 60kDa on SDS-PAGE.
Marcelo O Dietrich et al.
Trends in neurosciences, 36(2), 65-73 (2013-01-16)
The past 20 years witnessed an enormous leap in understanding of the central regulation of whole-body energy metabolism. Genetic tools have enabled identification of the region-specific expression of peripheral metabolic hormone receptors and have identified neuronal circuits that mediate the
Krishna Lamichhane et al.
Journal of environmental monitoring : JEM, 14(10), 2557-2565 (2012-08-30)
Elevated concentrations of estrogens in natural waters pose a significant threat to public health and aquatic ecosystems. Both natural (estrone, 17β-estradiol and estriol) and synthetic (17α ethynylestradiol) estrogens, ubiquitous in wastewater effluents and receiving waters, have been shown to affect
Nina Sneitz et al.
Drug metabolism and disposition: the biological fate of chemicals, 41(3), 582-591 (2013-01-05)
The glucuronidation of estriol, 16-epiestriol, and 17-epiestriol by the human UDP-glucuronosyltransferases (UGTs) of subfamilies 1A, 2A, and 2B was examined. UGT1A10 is highly active in the conjugation of the 3-OH in all these estriols, whereas UGT2B7 is the most active
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