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等级
certified reference material
质量水平
表单
liquid
特点
Snap-N-Spike®/Snap-N-Shoot®
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
浓度
1.0 mg/mL in methanol (as free base)
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
clinical testing
包装形式
single component solution
储存温度
−20°C
SMILES字符串
CN(C([2H])([2H])[2H])CC/C=C1C2=C(C=CC=C2)COC3=C/1C=CC=C3.[H]Cl
InChI
1S/C19H21NO.ClH/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19;/h3-6,8-12H,7,13-14H2,1-2H3;1H/b17-11-;/i1D3;
InChI key
MHNSPTUQQIYJOT-JSMHCMNYSA-N
一般描述
Doxepin is a tricyclic antidepressant used for the treatment of sleep maintenance. This internal standard is applicable for doxepin testing or isotope dilution methods by GC/MS or LC/MS for clinical toxicology, urine drug testing, or forensic analysis applications.
应用
- High-throughput protein precipitation method for doxepin analysis: A study presented a protein precipitation method using a 96-well plate to determine doxepin and nordoxepin levels in human plasma, employing LC-MS/MS, highlighting the utility of stable isotope-labeled doxepin for quantitative analysis in clinical settings (Margaryan et al., 2020).
- LC-MS-MS analysis of neuroleptics including doxepin: Research detailed the use of LC-MS-MS for analyzing neuroleptics like doxepin in hair samples from psychiatric patients, demonstrating the method′s effectiveness for long-term medication monitoring (Weinmann et al., 2002).
- Detection of doxepin in hair following therapy: A study investigated the detection of doxepin and its major metabolite in hair, providing a methodological foundation for forensic and clinical assessments of drug therapy adherence using hair samples (Negrusz et al., 1998).
法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
靶器官
Eyes
储存分类代码
3 - Flammable liquids
WGK
WGK 1
闪点(°F)
49.5 °F - closed cup
闪点(°C)
9.7 °C - closed cup
法规信息
危险化学品
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