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Merck
CN

D-055

N-Desethylamiodarone hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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关于此项目

经验公式（希尔记法）:
C23H26ClI2NO3
化学文摘社编号:
96027-74-6
分子量:
653.72
NACRES:
NA.24
PubChem Substance ID:
329798619
UNSPSC Code:
41116107
EC Number:
200-659-6
MDL number:
MFCD08060094

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产品名称

N-Desethylamiodarone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

InChI key

OCQPMJVGWGJLLG-UHFFFAOYSA-N

InChI

1S/C23H25I2NO3.ClH/c1-3-5-9-20-21(16-8-6-7-10-19(16)29-20)22(27)15-13-17(24)23(18(25)14-15)28-12-11-26-4-2;/h6-8,10,13-14,26H,3-5,9,11-12H2,1-2H3;1H

SMILES string

IC1=CC(C(C2=C(CCCC)OC3=CC=CC=C23)=O)=CC(I)=C1OCCNCC.Cl

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol (as free base)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

Quality Level

300

相关类别

General description

A Certified Spiking Solution® for use in therapeutic drug monitoring analyses by HPLC or LCMS. N-Desethylamiodarone is the primary, active metabolite of amiodarone, an antiarrhythmic agent marketed as Pacerone®, Cordarone®, Aratac, and Atlansil and monitored by clinical labs to ensure patients remain within the drugs therapeutic range.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Cordarone is a registered trademark of Sanofi S.A.
Pacerone is a registered trademark of Upsher-Smith Laboratories, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

存储类别

3 - Flammable liquids

wgk

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

法规信息

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Melissa K Passarelli et al.
Analytical chemistry, 87(13), 6696-6702 (2015-05-30)
Detecting metabolites and parent compound within a cell type is now a priority for pharmaceutical development. In this context, three-dimensional secondary ion mass spectrometry (SIMS) imaging was used to investigate the cellular uptake of the antiarrhythmic agent amiodarone, a phospholipidosis-inducing

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