推荐产品
等级
certified reference material
质量水平
表单
liquid
特点
Snap-N-Spike®/Snap-N-Shoot®
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
浓度
1.0 mg/mL in methanol (as free base)
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
clinical testing
包装形式
single component solution
储存温度
−20°C
SMILES字符串
Fc1ccc(cc1)[C@@]2(OCc3c2ccc(c3)C#N)CCCNC
InChI
1S/C19H19FN2O/c1-22-10-2-9-19(16-4-6-17(20)7-5-16)18-8-3-14(12-21)11-15(18)13-23-19/h3-8,11,22H,2,9-10,13H2,1H3/t19-/m0/s1
InChI key
PTJADDMMFYXMMG-IBGZPJMESA-N
一般描述
N-去甲基西酞普兰是SSRI抗抑郁药西酞普兰的一种活性代谢产物。西酞普兰在美国和加拿大以Celexa®的名义进行销售,可用于治疗与情绪障碍相关的重度抑郁症。
应用
- Reference concentrations for forensic and clinical toxicology:N-Desmethylcitalopram hydrochloride is used as a reference compound in neuropharmacological and toxicological studies (Nedahl et al., 2018).
法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Celexa is a registered trademark of H. Lundbeck A/S
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
相关产品
产品编号
说明
价格
警示用语:
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
靶器官
Eyes,Central nervous system
储存分类代码
3 - Flammable liquids
WGK
WGK 2
闪点(°F)
49.5 °F - closed cup
闪点(°C)
9.7 °C - closed cup
法规信息
危险化学品
Scientific reports, 10(1), 20203-20203 (2020-11-21)
Brown adipose tissue (BAT) thermogenesis is considered a potential target for treatment of obesity and diabetes. In vitro data suggest dopamine receptor signaling as a promising approach; however, the biological relevance of dopamine receptors in the direct activation of BAT
Cell reports. Medicine, 2(2), 100202-100202 (2021-03-06)
The aberrant expression of dopamine receptors (DRDs) in acute myeloid leukemia (AML) cells has encouraged the repurposing of DRD antagonists such as thioridazine (TDZ) as anti-leukemic agents. Here, we access patient cells from a Phase I dose escalation trial to
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