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Merck
CN
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安全信息

D-034

Supelco

右啡烷 酒石酸酯 溶液

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

经验公式（希尔记法）:
C21H29NO7
CAS号:
143-98-6
分子量:
407.46
EC 号:
200-659-6
MDL编号:
MFCD00151495
UNSPSC代码:
41116107
PubChem化学物质编号:
329798600
NACRES:
NA.24

等级

certified reference material

质量水平

300

形式

liquid

特点

Snap-N-Spike®/Snap-N-Shoot®

包装

ampule of 1 mL

制造商/商品名称

Cerilliant®

浓度

1.0 mg/mL in methanol (as free base)

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

应用

forensics and toxicology

格式

single component solution

储存温度

−20°C

SMILES字符串

O[C@H]([C@@H](O)C(O)=O)C(O)=O.CN1CC[C@@]23CCCC[C@@H]2[C@@H]1Cc4ccc(O)cc34

InChI

1S/C17H23NO.C4H6O6/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17;5-1(3(7)8)2(6)4(9)10/h5-6,11,14,16,19H,2-4,7-10H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t14-,16+,17+;1-,2-/m11/s1

InChI key

RWTWIZDKEIWLKQ-XCPWPWHNSA-N

相关类别

一般描述

Snap-N-Spike®参比溶液适用于临床毒理学、法医分析、P450试验或药物研究的LC/MS或GC/MS应用。右啡烷是血液中右美沙芬的主要代谢产物。右美沙芬是许多非处方感冒和咳嗽中的活性成分，被娱乐性地用作致幻剂，其作用类似于氯胺酮和苯环利定（PCP）。

应用


  • Anti-Persister Activity Against Borrelia burgdorferi: Dextrorphan tartrate was evaluated for its anti-persister activity against Borrelia burgdorferi, demonstrating potential as an effective agent in the treatment of persistent Lyme disease infections. This research underscores its pharmacodynamic relevance and encourages further exploration in neuropharmacological contexts (Feng et al., 2015).

  • High-Performance Liquid Chromatography in Pharmacokinetics: Dextrorphan tartrate was used in a sensitive assay involving high-performance liquid chromatography for the detection of metoprolol and its major metabolite in human plasma. This method highlights its importance as an analytical standard in pharmacokinetic studies, aiding in the understanding of drug metabolism and disposition (Mistry et al., 1998).

  • Opioid Receptor Binding: The interaction of dextrorphan tartrate with opioid receptors was examined, showing that it binds to opioid receptors in guinea-pig brain membranes and acts as an antagonist in myenteric plexus. This research supports its utility in opioid receptor studies, particularly in examining opioid antagonistic properties (Goldstein & Naidu, 1990).

法律信息

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

靶器官

Eyes

WGK

WGK 1

闪点(°F)

closed cup

闪点(°C)

closed cup

法规信息

监管及禁止进口产品

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