推荐产品
等级
certified reference material
质量水平
表单
liquid
特点
SNAP-N-SPIKE®, SNAP-N-SHOOT®
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
浓度
1.0 mg/mL in methanol
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
forensics and toxicology
包装形式
single component solution
储存温度
−20°C
SMILES字符串
N1(C(CCC1=O)c2cnccc2)C([2H])([2H])[2H]
InChI
1S/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3/i1D3
InChI key
UIKROCXWUNQSPJ-FIBGUPNXSA-N
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一般描述
可替宁是存在于烟草中的一种生物碱，也是尼古丁的主要尿液代谢物。这种稳定标记的内标适用于尼古丁测试或尼古丁生物标记物的临床和诊断测试，通过GC/MS或LC-MS/MS法定量尿液、血液和唾液中的可替宁水平。
应用
- (±)-Cotinine-d₃ solution in nicotine metabolism research: This stable isotope-labeled compound is utilized in the HPLC-MS analysis of nicotine and cotinine across various biological matrices, highlighting its critical role in advancing our understanding of nicotine metabolism and exposure in biomedical studies (Jin et al., 2022).
- Biomarker analysis in passive smoking: Cotinine-d₃ serves as an internal standard in the precise quantification of urinary cotinine, aiding in the assessment of second-hand smoke exposure, particularly in pediatric health studies (Wang et al., 2014).
- Enhanced analytical techniques for smoking cessation: Employed in a sophisticated UPLC-MS/MS setup, cotinine-d₃ is crucial for quantifying smoking-related biomarkers in clinical trials aimed at evaluating smoking cessation interventions, ensuring accurate and sensitive biomarker tracking (Dobrinas et al., 2011).
法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
靶器官
Eyes
储存分类代码
3 - Flammable liquids
WGK
WGK 2
闪点(°F)
51.8 °F - closed cup
闪点(°C)
11.0 °C - closed cup
法规信息
危险化学品
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