跳转至内容
Merck
CN
所有图片(1)

文件

安全信息

C-017

Supelco

(±)-可替宁-D3标准液 CRM 溶液

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

登录查看公司和协议定价
所有图片(1)
别名:
(+/-)-可替宁-D3标准液 CRM 溶液
经验公式（希尔记法）:
C10H9D3N2O
CAS号:
110952-70-0
分子量:
179.23
EC 号:
200-659-6
MDL编号:
MFCD00083283
UNSPSC代码:
41116107
PubChem化学物质编号:
329774766
NACRES:
NA.24

等级

certified reference material

质量水平

300

形式

liquid

特点

SNAP-N-SPIKE®, SNAP-N-SHOOT®

包装

ampule of 1 mL

制造商/商品名称

Cerilliant®

浓度

100 μg/mL in methanol

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

应用

forensics and toxicology

格式

single component solution

储存温度

−20°C

InChI

1S/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3/i1D3

InChI key

UIKROCXWUNQSPJ-FIBGUPNXSA-N

正在寻找类似产品? 访问 产品对比指南

相关类别

一般描述

可替宁是一种在烟草中发现的生物碱，也是尼古丁的主要尿液代谢产物。在通过GC/MS或LC-MS/MS对尼古丁或尼古丁生物标记物的临床和诊断测试中，这种稳定标记的内标适用于尿液、血液和唾液中可替宁水平的定量。

应用



  • Advanced mass spectrometry applications: A review covers high-performance liquid chromatography-mass spectrometry (HPLC-MS) methods, including the use of (±)-Cotinine-d₃ for the analysis of nicotine and its metabolite cotinine across various biological matrices, highlighting its role in accurate biomarker quantification (Jin et al., 2022).


  • Exposure assessment in passive smoking: The study employs stable isotope dilution gas chromatography-triple quadrupole mass spectrometry with (±)-Cotinine-d₃ to determine urinary cotinine levels in children exposed to passive smoking, demonstrating its efficacy in environmental health research (Wang et al., 2014).


  • Nicotine metabolism in special populations: Research utilizes a liquid chromatography-tandem mass spectrometry method to investigate nicotine metabolism in HIV-1-positive smokers, using (±)-Cotinine-d₃ to track metabolic variations, thereby aiding in personalized medicine approaches (Earla et al., 2014).


  • Automated LC-MS-MS for cotinine detection: The development of an automated solid-phase extraction method for LC-MS-MS highlights the use of (±)-Cotinine-d₃ for streamlined and precise cotinine detection, applicable in clinical toxicology and therapeutic monitoring (Dunlop et al., 2014).


  • Quantitative analysis in smoking cessation: A sensitive UPLC-tandem mass spectrometry procedure quantifies nicotine, cotinine, and their metabolites in plasma using (±)-Cotinine-d₃ as an internal standard, crucial for clinical studies on smoking cessation (Dobrinas et al., 2011).


法律信息

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

相关产品

产品编号
说明
价格

A-097

(+)-毒藜碱 盐酸盐 溶液, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

A-100

Anabasine-d4 hydrochloride solution, 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

C-016

(-)-可替宁 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

C-035

(±)-可替宁-D3标准液 CRM 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

N-008

S(−)-尼古丁 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

N-048

(±)-烟碱-D4标准液 CRM 溶液, 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

N-071

(±)-降烟碱 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

N-072

(±)-Nornicotine-d4, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

N-075

(±)-N′-亚硝基降烟碱 (NNN) 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

N-076

甲基亚硝胺基吡啶基丁酮(NNK)标准液 CRM 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

N-077

(S)-N-Nitrosoanabasine (NAB) solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

靶器官

Eyes

WGK

WGK 1

闪点(°F)

closed cup

闪点(°C)

closed cup

法规信息

危险化学品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门