推荐产品
等级
certified reference material
质量水平
形式
liquid
特点
SNAP-N-SPIKE®, SNAP-N-SHOOT®
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
drug control
Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IB (Portugal)
浓度
1.0 mg/mL in acetonitrile
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
forensics and toxicology
格式
single component solution
储存温度
−20°C
SMILES字符串
CN1[C@@]2([H])[C@@H](C(OCC)=O)[C@@H](OC(C3=CC=CC=C3)=O)C[C@]1([H])CC2
InChI
1S/C18H23NO4/c1-3-22-18(21)16-14-10-9-13(19(14)2)11-15(16)23-17(20)12-7-5-4-6-8-12/h4-8,13-16H,3,9-11H2,1-2H3/t13-,14+,15-,16+/m0/s1
InChI key
NMPOSNRHZIWLLL-XUWVNRHRSA-N
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一般描述
A certified Snap-N-Spike® solution suitable for use as starting material in calibrators and controls for GC/MS or LC/MS methods in clinical toxicology, forensic analysis, or urine drug testing. Cocaethylene is the ethyl ester of benzoylecgonine. This benzoylecgonine analog is formed during cocaine metabolism when ethanol is present.
应用
- Innovative forensic detection methods: Development of a new analytical method using magnetic nanoparticles for the detection of cocaine, its antidepressants, and metabolites in postmortem blood highlights advances in forensic toxicology. This method, including the analysis of cocaethylene, improves the accuracy and efficiency of drug testing in forensic investigations (de Souza Schwarz et al., 2024).
- Quantitative wastewater analysis for public health: This research involves quantitative analysis of wastewater to monitor drugs of abuse, including cocaine and its potent metabolite cocaethylene. It serves as an essential method for understanding public health trends and the effectiveness of drug use interventions within communities (Frankenfeld et al., 2023).
法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
相关产品
产品编号
说明
价格
警示用语：
Danger
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
WGK
WGK 2
闪点(°F)
35.6 °F
闪点(°C)
2 °C
法规信息
监管及禁止进口产品
Ellen D Herbst et al.
Experimental and clinical psychopharmacology, 19(2), 95-104 (2011-04-06)
Ethanol alters the hepatic biotransformation of cocaine, resulting in transesterification to a novel active metabolite, cocaethylene. Because of first pass metabolism, oral drug administration might be expected to produce relatively larger concentrations of cocaethylene than would intravenous or smoked administration.
Xavier Joya et al.
Forensic science international, 196(1-3), 38-42 (2010-01-09)
We describe the development and validation of a method for the quantification of drugs of abuse, using gas chromatography-mass spectrometry (GC/MS), in human placenta. Concentration ranges covered were 5-500 ng/g for amphetamine, methamphetamine, MDMA, methadone, cocaine, benzoylecgonine, cocaethylene, morphine, 11-nor-9-carboxy-delta-9-tetrahydrocannabinol
Laura Mercolini et al.
Journal of chromatography. A, 1217(46), 7242-7248 (2010-10-12)
An original HPLC method coupled to spectrofluorimetric detection is presented for the simultaneous analysis in dried blood spots (DBS) of cocaine and two important metabolites, namely benzoylecgonine (its main metabolite) and cocaethylene (the active metabolite formed in the presence of
Yao Lu et al.
Forensic science international, 189(1-3), 54-59 (2009-05-22)
A reliable, alternative screening method for detection of cocaine and its metabolites, benzoylecgonine and cocaethylene in urine is demonstrated using solid phase extraction (SPE) coupled with ion mobility spectrometry (IMS). Data analysis with alternating least squares (ALS) is used to
Sue Paterson et al.
Forensic science international, 194(1-3), 94-96 (2009-11-21)
In post-mortem work, blood is a potential source of external contamination of hair. The present study was carried out to investigate the amount of drug absorbed into hair which has been contaminated with blood containing either cocaine or BE. Solutions
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