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安全信息

C-008

Supelco

可卡因标准液 溶液

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

经验公式（希尔记法）:
C17H21NO4
CAS号:
50-36-2
分子量:
303.35
MDL编号:
MFCD00056906
UNSPSC代码:
41116107
PubChem化学物质编号:
329774761
NACRES:
NA.24

等级

certified reference material

质量水平

300

表单

liquid

特点

SNAP-N-SPIKE®, SNAP-N-SHOOT®

包装

ampule of 1 mL

制造商/商品名称

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IB (Portugal)

浓度

1.0 mg/mL in acetonitrile

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

应用

forensics and toxicology

包装形式

single component solution

储存温度

−20°C

SMILES字符串

COC(=O)[C@H]1[C@H](C[C@@H]2CC[C@H]1N2C)OC(=O)c3ccccc3

InChI

1S/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/t12-,13+,14-,15+/m0/s1

InChI key

ZPUCINDJVBIVPJ-LJISPDSOSA-N

一般描述

经认证的加标溶液®适用于法医分析、尿液药物测试或临床毒理学的LC/MS或GC/MS试验应用。可卡因是从古柯植物的叶子中提取的莨菪烷类生物碱和非法药物。这种流行的消遣性药物是中枢神经系统的强大兴奋剂，具有食欲抑制剂和局部麻醉特性。

应用


  • High-purity cocaine hydrochloride for scientific research: An innovative analytical method was developed using magnetic nanoparticles for the forensic detection of cocaine and its metabolites in postmortem blood samples, underlining its precision in detecting and quantifying cocaine in complex biological matrices (de Souza Schwarz et al., 2024).


法律信息

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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象形图

FlameExclamation mark
GHS02,GHS07

警示用语：

Danger

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

储存分类代码

3 - Flammable liquids

WGK

WGK 2

闪点(°F)

35.6 °F - closed cup

闪点(°C)

2 °C - closed cup

法规信息

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Coca science seeks an answer in kilos.
Antonio Regalado
Science (New York, N.Y.), 341(6145), 453-453 (2013-08-03)
Carlos Manuel Lima Reis da Silva et al.
Journal of psychoactive drugs, 45(2), 195-198 (2013-08-03)
The topic of ophthalmic use of cocaine in clinical practice has a long history; nevertheless, the possible influence and pathways of action of inhaled cocaine in the human eye remain unknown. This study evaluates the effect of snorted cocaine in
Watchareewan Thongsaard et al.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 96 Suppl 1, S85-S89 (2013-06-04)
Thunbergia laurifolia Linn. (TL) is a herbal medicine used as an antidote for several poisonous agents in Thai traditional medicine. TL were reported not only to significantly increase potassium-stimulated dopamine release from rat striatal slices but also potentiated the effect
Risheng Xu et al.
Neuron, 78(4), 623-630 (2013-05-31)
Cocaine's behavioral-stimulant effects derive from potentiation of synaptic signaling by dopamine and serotonin leading to transcriptional alterations in postsynaptic cells. We report that a signaling cascade involving nitric oxide (NO) and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mediates cocaine's transcriptional and behavioral actions.
W Pitchot et al.
Revue medicale de Liege, 68(5-6), 294-297 (2013-07-31)
Cocaine is the second most commonly used illicit drug after cannabis in the general population. Cocaine is a powerful stimulating agent of the central nervous system and a highly addictogenic drug. Somatic and psychiatric consequences of cocaine addiction are major
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