推荐产品
等级
certified reference material
表单
liquid
特点
Snap-N-Spike®/Snap-N-Shoot®
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
浓度
25 μg/mL in methanol (each analyte)
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
pharmaceutical (small molecule)
包装形式
multi-component solution
储存温度
−20°C
一般描述
Acetaminophen is formed as a metabolic product of phenacetin and is a well-known drug used in the treatment of pain and fever due to its effective central analgesic and antipyretic properties. It is also the only analgesic drug that is non-opioid and available in the oral, rectal, and intravenous formulation forms. It has been posited to inhibit the synthesis of prostaglandins and exhibit a mode of action similar to nonsteroidal anti-inflammatory drugs (NSAIDs).
应用
Acetaminophen Impurity Mixture solution may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
分析物
说明
Acetaminophen Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material
Acetaminophen Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material
Acetaminophen Related Compound D, Pharmaceutical Secondary Standard; Certified Reference Material
Acetaminophen Related Compound F, Pharmaceutical Secondary Standard; Certified Reference Material
Acetaminophen, Pharmaceutical Secondary Standard; Certified Reference Material
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
靶器官
Eyes
储存分类代码
3 - Flammable liquids
WGK
WGK 2
闪点(°F)
49.5 °F - closed cup
闪点(°C)
9.7 °C - closed cup
法规信息
监管及禁止进口产品
Acetaminophen poisoning and toxicity
Rumack BH and Matthew H
Pediatrics, 55(6), 871- 876 (1975)
Acetaminophen-induced hepatotoxicity
James LP, et al.
Drug Metabolism and Disposition, 31(12), 1499- 1506 (2003)
Intravenous paracetamol (acetaminophen)
Duggan ST and Scott LJ
Drugs, 69(1), 101- 113 (2009)
Central analgesic effect of acetaminophen but not of aspirin
Piletta P, et al.
Clinical Pharmacology and Therapeutics, 49(4), 350- 354 (1991)
Paracetamol (Acetaminophen): mechanisms of action
Anderson BJ
Pediatric Anesthesia, 18(10), 915- 921 (2008)
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