等级
certified reference material
质量水平
形式
liquid
特点
SNAP-N-SPIKE®, SNAP-N-SHOOT®
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
浓度
100 μg/mL in methanol (as free base)
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
forensics and toxicology
格式
single component solution
储存温度
−20°C
InChI
1S/C10H14N2.ClH/c1-2-7-12-10(5-1)9-4-3-6-11-8-9;/h3-4,6,8,10,12H,1-2,5,7H2;1H/i3D,4D,6D,8D;
InChI key
VTMZQNZVYCJLGG-BHBAGPQMSA-N
一般描述
Anabasine is a nicotine alkaloid present in tobacco products and used as an indicator of smoking or tobacco use. This certified Snap-N-Spike® Solution is suitable for use as an internal standard for quantification of anabasine levels in urine or other matrices for nicotine testing or environmental monitoring applications by LC-MS/MS or GC/MS.
应用
- Anabasine-d₄ hydrochloride stable isotope-labeled compound: A study on mesoporous titanium nanoparticles loaded with berberine hydrochloride explores UV-triggered drug release, demonstrating the utility of Anabasine-d₄ hydrochloride in enhancing antibiotic delivery and efficacy, especially in bacterial infections (Zuo et al., 2024).
- High purity Anabasine-d₄ hydrochloride for analytical research: Research on berberine hydrochloride-loaded liposomes-in-gel assesses antioxidant activity and eczema treatment, with Anabasine-d₄ hydrochloride playing a critical role in stabilizing formulations and improving therapeutic outcomes (Shen et al., 2024).
- Anabasine-d₄ HCl solution for nicotine receptor studies: Anabasine-d₄ hydrochloride is highlighted in a study on synthetic routes and clinical applications of small-molecule EGFR inhibitors for cancer therapy, emphasizing its importance in oncological research and receptor interaction studies (Wang et al., 2024).
- Deuterated Anabasine hydrochloride for mass spectrometry: A publication on poly(lactic-co-glycolic acid) nanoparticles investigates drug release behaviors co-loaded with hydrophilic and hydrophobic drugs, where Anabasine-d₄ hydrochloride is crucial as an internal standard in mass spectrometry to ensure accurate pharmacokinetic profiles (Wang et al., 2024).
- Anabasine-d₄ as an internal standard in pharmacokinetic analysis: Anabasine-d₄ hydrochloride′s role as an internal standard is underscored in a study on the pharmacokinetics of traditional Chinese medicine in treating primary Sjögren syndrome, providing insights into complex bioanalytical methodologies (Chen et al., 2024).
法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
靶器官
Eyes
WGK
WGK 2
闪点(°F)
49.5 °F
闪点(°C)
9.7 °C
法规信息
危险化学品
Safiyye Kavak et al.
Frontiers in chemistry, 8, 622567-622567 (2021-02-12)
We incorporated a water-stable ionic liquid (IL), 1-butyl-3-methylimidazolium hexafluorophosphate, [BMIM][PF6], into a water-stable metal-organic framework (MOF), MIL-53(Al), to generate the [BMIM][PF6]/MIL-53(Al) composite. This composite was examined for water purification by studying its capacity for methylene blue (MB) and methyl orange
Robert Minkner et al.
Journal of nanobiotechnology, 18(1), 159-159 (2020-11-08)
Purification of recombinant proteins is often a challenging matter because high purity and high recovery are desired. If the expressed recombinant protein is also in a complex matrix, such as from the silkworm expression system, purification becomes more challenging. Even
E A Holleran et al.
The Journal of cell biology, 135(6 Pt 2), 1815-1829 (1996-12-01)
Centractin (Arp1), an actin-related protein, is a component of the dynactin complex. To investigate potential functions of the protein, we used transient transfections to overexpress centractin in mammalian cells. We observed that the overexpressed polypeptide formed filamentous structures that were
Gordon J Troup et al.
PloS one, 10(4), e0122834-e0122834 (2015-04-10)
The roasting of coffee beans generates stable radicals within melanoidins produced by non-enzymatic browning. Roasting coffee beans has further been suggested to increase the antioxidant (AO) capacity of coffee brews. Herein, we have characterized the radical content and AO capacity
Nuno Alexandre et al.
Journal of biomedical materials research. Part A, 103(4), 1366-1379 (2014-07-22)
Polyvinyl alcohol hydrogel (PVA) is a water-soluble synthetic polymer that is commonly used in biomedical applications including vascular grafting. It was argued that the copolymerization of PVA with dextran (Dx) can result in improvement of blood-biomaterial interactions. The focus of
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