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Merck
CN

A-009

Supelco

6-乙酰吗啡标准液 溶液

1 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

别名:

6-乙酰吗啡 溶液

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About This Item

经验公式(希尔记法):
C19H21NO4
CAS号:
分子量:
327.37
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

certified reference material

质量水平

形式

liquid

特点

SNAP-N-SPIKE®. SNAP-N-SHOOT®

包装

ampule of 1 mL

制造商/商品名称

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

浓度

1 mg/mL in acetonitrile

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

应用

forensics and toxicology

格式

single component solution

储存温度

2-8°C

SMILES字符串

CN1CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@@H]2C=C[C@@H]4OC(C)=O)c35

InChI

1S/C19H21NO4/c1-10(21)23-15-6-4-12-13-9-11-3-5-14(22)17-16(11)19(12,18(15)24-17)7-8-20(13)2/h3-6,12-13,15,18,22H,7-9H2,1-2H3/t12-,13+,15-,18-,19-/m0/s1

InChI key

JJGYGPZNTOPXGV-SSTWWWIQSA-N

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一般描述

6-乙酰吗啡,也称为 6-单乙酰吗啡或 6-MAM,是海洛因的活性代谢产物,并且是海洛因使用的生物标志物。该经过认证的加标溶液®适合用作法医分析、临床毒理学、尿液药物测试或止痛处方监测中 GC/MS 或 LC/MS 方法的校准和对照的起始材料。由于尿液的检测窗口短,因此检测相对较难。海洛因给药后(静脉内)的几分钟内唾液中就会出现 6-乙酰吗啡,并且发现其浓度要高于血浆。

应用


  • Forensic toxicology reference: 6-Acetylmorphine is used as a key analytical reference material in forensic toxicology to identify heroin use in morphine-positive urine specimens, aiding in the differentiation between pharmaceutical and illicit opioid consumption (Vikingsson et al., 2024).

  • Opiate research chemical: This compound serves as a high-purity standard for opioid research, facilitating the study of opioid metabolism and the development of new analytical techniques in bioanalytical studies (Liu et al., 2024).

法律信息

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTIONS is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

相关产品

产品编号
说明
价格

象形图

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警示用语:

Danger

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

WGK

WGK 2

闪点(°F)

42.8 °F

闪点(°C)

6.0 °C

法规信息

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High prevalence of 6-acetylmorphine in morphine-positive oral fluid specimens.
Presley
Forensic Science International, 133(1-2) (2003)
Joseph Jones
Journal of Analytical Toxicology, 171-175 (2002)
Forensic drug testing for opiates: I. Detection of 6-acetylmorphine in urine as an indicator of recent heroin exposure; drug and assay considerations and detection times.
Cone EJ
Journal of Analytical Toxicology (1991)
Forensic Science International null
M Pravetoni et al.
Vaccine, 30(31), 4617-4624 (2012-05-16)
Opioid conjugate vaccines have shown promise in animal models as a potential treatment for opioid addiction. Individual vaccines are quite specific and each targets only a limited number of structurally similar opioids. Since opioid users can switch or transition between

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