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Merck
CN

A-006

Supelco

6-乙酰吗啡-D3标准液 CRM 溶液

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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别名:
6-乙酰吗啡-N-甲基-d3 溶液
经验公式(希尔记法):
C19D3H18NO4
分子量:
330.39
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

certified reference material

质量水平

形式

liquid

特点

SNAP-N-SPIKE®. SNAP-N-SHOOT®

包装

ampule of 1 mL

制造商/商品名称

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

浓度

100 μg/mL in acetonitrile

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

应用

forensics and toxicology

格式

single component solution

质量偏移

M+3

储存温度

−20°C

SMILES字符串

[2H]C([2H])([2H])N1CC[C@]23C4Oc5c(O)ccc(CC1C2C=C[C@@H]4OC(C)=O)c35

InChI

1S/C19H21NO4/c1-10(21)23-15-6-4-12-13-9-11-3-5-14(22)17-16(11)19(12,18(15)24-17)7-8-20(13)2/h3-6,12-13,15,18,22H,7-9H2,1-2H3/t12-,13+,15-,18-,19-/m0/s1/i2D3

InChI key

JJGYGPZNTOPXGV-VALGNVEGSA-N

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一般描述

适用于临床毒理学、法医学分析、尿液药物检测、疼痛处方监测和同位素稀释方法的 GC/MS 或 LC/MS 检测中定量测定 6-乙酰吗啡 (6-MAM) 水平的稳定标记内标物。也被称为 6-单乙酰吗啡,6-MAM 是海洛因的活性代谢产物和海洛因使用的生物标志物。

应用


  • Quantitative analysis of opiates in human fluids: A study employed 6-Acetylmorphine-d3 solution as part of a bioanalytical method using gas chromatography-triple quadrupole mass spectrometry for the precise quantification of opiates in human blood samples, highlighting its utility in forensic and clinical toxicology (Saad et al., 2019).

  • Enhanced opioid metabolite detection: Research integrated 6-Acetylmorphine-d3 solution in an electrospray LC-MS method with solid-phase extraction, significantly improving the accuracy of detecting opioid metabolites in urine. This method is vital for drug monitoring and pharmacokinetic studies (Svensson et al., 2007).

  • Forensic application in controlled drug programs: A study used 6-Acetylmorphine-d3 solution to establish dose-concentration relationships in hair from subjects in a controlled heroin-maintenance program, proving its essential role in forensic science for monitoring drug intake (Kintz et al., 1998).

  • Drug monitoring in clinical settings: The solution was also applied in a novel assay for the determination of opioids in blood and pericardial fluid, offering a robust tool for clinical diagnostics and forensic investigations (Ferreira et al., 2020).

法律信息

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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警示用语:

Danger

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

WGK

WGK 2

闪点(°F)

35.6 °F

闪点(°C)

2 °C

法规信息

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