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Merck
CN
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文件

安全信息

A-002

Supelco

(±)-Amphetamine-d5 (deuterium label on ring) solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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经验公式（希尔记法）:
C9D5H8N
CAS号:
65538-33-2
分子量:
140.24
EC 号:
200-659-6
MDL编号:
MFCD00673255
UNSPSC代码:
41116107
PubChem化学物质编号:
329770563
NACRES:
NA.24

等级

certified reference material

质量水平

300

形式

liquid

特点

SNAP-N-SPIKE®. SNAP-N-SHOOT®

包装

ampule of 1 mL

制造商/商品名称

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)

浓度

100 μg/mL in methanol

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

应用

forensics and toxicology

格式

single component solution

储存温度

−20°C

SMILES字符串

CC(N)CC1=C([2H])C([2H])=C([2H])C([2H])=C1[2H]

InChI

1S/C9H13N/c1-8(10)7-9-5-3-2-4-6-9/h2-6,8H,7,10H2,1H3/i2D,3D,4D,5D,6D

InChI key

KWTSXDURSIMDCE-VIQYUKPQSA-N

相关类别

一般描述

Amphetamine, a central nervous system stimulant, belongs to the phenethylamine clas. It is found in ADHD-treatment drugs such as Adderall®, Vyvanse®, and ProCentra®. It is also used for the treatment of narcolepsy. Because of its stimulant effect, amphetamine is used recreationally as a performance-enhancer and illicit drug. This stable-labeled internal standard is suitable for quantitation of amphetamine levels in urine, serum, or plasma by LC/MS or GC/MS for urine drug testing, clinical toxicology, forensic analysis, or sports testing.

应用


  • Amphetamine-d5 solution as a mass spectrometry internal standard: The deuterium-labeled amphetamine (amphetamine-d5) serves as a precise internal standard for mass spectrometry, enhancing the accuracy of quantitative analyses in forensic toxicology and pharmaceutical testing. This application is crucial for identifying and quantifying amphetamine in biological samples, as demonstrated in a method developed for detecting psychoactive drugs (Barone et al., 2023).

  • Stable isotope-labeled amphetamine for pharmaceutical research: Amphetamine-d5 is employed in pharmaceutical research to investigate the metabolic pathways of amphetamines. Its stable isotopic label allows for the tracking of amphetamine metabolites in complex biological matrices, offering insights into drug metabolism and pharmacokinetics (Alhazmi et al., 2020).

  • Deuterated amphetamine in analytical chemistry: As a high-purity analytical reference material, amphetamine-d5 is used to calibrate and validate chromatographic and mass spectrometric methods. This ensures the reliability and reproducibility of analytical assays in both clinical and forensic settings, critical for drug monitoring and therapeutic drug management (Mohamed et al., 2016).

法律信息

Adderall is a registered trademark of Richwood Pharmaceutical Company, Inc.
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
ProCentra is a registered trademark of Outlook Pharmaceuticals, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Vyvanse is a registered trademark of Shire, LLC

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警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

靶器官

Eyes

WGK

WGK 1

闪点(°F)

49.5 °F

闪点(°C)

9.7 °C

法规信息

监管及禁止进口产品

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