推荐产品
形式
methanol solution
包装
pkg of 1 × 1 mL (LM4103-1EA)
制造商/商品名称
Avanti Polar Lipids LM4103
浓度
~10 μg/mL (Refer to C of A for lot specific concentration. )
运输
dry ice
储存温度
−20°C
SMILES字符串
[H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)C3=C[C@H]2O)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCCC([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H]
一般描述
7α-hydroxycholesterol is an oxysterol synthesized by the oxidation of the side chain of cholesterol. It is the precursor of bile acid.
应用
7α-hydroxycholesterol (D7) may be used:
- as a deuterated sterol standard for the extraction of lipids from cultured cells
- in liquid chromatography-high-resolution mass spectrometry method (LC-MS/HR-MS) for the quantification
- to synthesize d4-7 -hydroxy-3-oxo-4-cholestenoic acid (d4-7-HOCA)
包装
2 mL Amber Glass Sealed Ampule (LM4103-1EA)
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
靶器官
Eyes
WGK
WGK 2
法规信息
危险化学品
Quantification of the 15 major human bile acids and their precursor 7? -hydroxy-4-cholesten-3-one in serum by liquid chromatography--tandem mass spectrometry
Steiner C, et al.
Journal of Chromatography. B, Biomedical Applications, 878(28), 2870-2880 (2010)
Oxysterols in the pathogenesis of major chronic diseases
Poli G, et al.
Redox Biology, 1(1), 125-130 (2013)
7 ? -hydroxy-3-oxo-4-cholestenoic acid in cerebrospinal fluid reflects the integrity of the blood-brain barrier
Saeed A, et al.
Journal of Lipid Research, 55(2), 313-318 (2014)
Extraction and analysis of sterols in biological matrices by high performance liquid chromatography electrospray ionization mass spectrometry
McDonald J, et al.
Test, 432, 145-170 (2007)
Jeffrey G McDonald et al.
Methods in enzymology, 432, 145-170 (2007-10-24)
We describe the development of a high performance liquid chromatography mass spectrometry (HPLC-MS) method that allows the identification and quantitation of sterols in mammalian cells and tissues. Bulk lipids are extracted from biological samples by a modified Bligh/Dyer procedure in
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