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Merck
CN

LM1503

Avanti

21:0-22:6 PI

Avanti Polar Lipids LM1503, methanol solution

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别名:
1-heneicosanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt)
经验公式(希尔记法):
C52H92NO13P
分子量:
970.26
UNSPSC代码:
12352211
NACRES:
NA.25

形式

methanol solution

包装

pkg of 1 × 1 mL (LM1503-1EA)

制造商/商品名称

Avanti Polar Lipids LM1503

浓度

~10 μg/mL (Refer to C of A for lot specific concentration. )

应用

lipidomics
metabolomics

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(OC(CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)=O)COC(CCCCCCCCCCCCCCCCCCCC)=O.[NH4+]

应用

21:0-22:6 PI or 1-heneicosanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-(1′-myo-inositol) has been used as an internal standard for phospholipid quantification using electrospray ionization tandem mass spectrometry (ESI-MS/MS) and for lipid quantification using liquid chromatography mass spectrometry (LC-MS).

包装

2 mL Amber Glass Sealed Ampule (LM1503-1EA)

警示用语:

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

靶器官

Eyes,Central nervous system

WGK

WGK 2

法规信息

危险化学品

分析证书(COA)

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Christian Klose et al.
The Journal of biological chemistry, 285(39), 30224-30232 (2010-07-22)
The lipid raft concept proposes that biological membranes have the potential to form functional domains based on a selective interaction between sphingolipids and sterols. These domains seem to be involved in signal transduction and vesicular sorting of proteins and lipids.
Dharmaraja Allimuthu et al.
Cell chemical biology, 26(4), 593-599 (2019-02-19)
Small molecules that promote oligodendrocyte formation have been identified in "drug repurposing" screens to nominate candidate therapeutics for diseases in which myelin is lost, including multiple sclerosis. We recently reported that many such molecules enhance oligodendrocyte formation not by their
Ulrike Bruning et al.
Cell metabolism, 28(6), 866-880 (2018-08-28)
The role of fatty acid synthesis in endothelial cells (ECs) remains incompletely characterized. We report that fatty acid synthase knockdown (FASNKD) in ECs impedes vessel sprouting by reducing proliferation. Endothelial loss of FASN impaired angiogenesis in vivo, while FASN blockade reduced
Alexander Fauland et al.
Journal of lipid research, 52(12), 2314-2322 (2011-10-01)
This work aims to combine chromatographic retention, high mass resolution and accuracy, MS/MS spectra, and a package for automated identification and quantitation of lipid species in one platform for lipidomic analysis. The instrumental setup elaborated comprises reversed-phase HPLC coupled to

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