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安全信息

LM1502

Avanti

17:0-20:4 PI

Avanti Research™ - A Croda Brand LM1502, methanol solution

别名:

1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt)

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About This Item

经验公式（希尔记法）:
C46H84NO13P
CAS号:
1246304-59-5
分子量:
890.13
UNSPSC代码:
12352211
NACRES:
NA.25

表单

methanol solution

包装

pkg of 1 × 1 mL (LM1502-1EA)

制造商/商品名称

Avanti Research™ - A Croda Brand LM1502

浓度

~10 μg/mL (Refer to C of A for lot specific concentration. )

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O.[NH4+]

InChI

1S/C46H81O13P.H3N/c1-3-5-7-9-11-13-15-17-19-20-21-23-25-27-29-31-33-35-40(48)58-38(37-57-60(54,55)59-46-44(52)42(50)41(49)43(51)45(46)53)36-56-39(47)34-32-30-28-26-24-22-18-16-14-12-10-8-6-4-2;/h11,13,17,19,21,23,27,29,38,41-46,49-53H,3-10,12,14-16,18,20,

InChI key

AUAQSQQWFOADLK-AQBZCRPISA-N

相关类别

一般描述

Phosphatidylinositol (PI) is soluble in water and chloroform/methanol. It is commonly found in animal tissues and bacteria.

应用

17:0-20:4 PI has been used as an internal standard for:
  • lipid extraction from isolated pure mitochondria by modified Bligh and Dyer method
  • lipid quantitation using liquid chromatography-mass spectrometry (LC-MS)
  • the analysis of phosphatidylinositol (PI) and phosphatidylinositol bisphosphates (PI(3,4)P2 and PI(4,5)P2) by high performance liquid chromatography-mass spectrometry (HPLC-MS)

包装

2 mL Amber Glass Sealed Ampule (LM1502-1EA)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

靶器官

Eyes

储存分类代码

3 - Flammable liquids

WGK

WGK 2

闪点(°F)

49.5 °F - closed cup

闪点(°C)

9.7 °C - closed cup

法规信息

危险化学品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jiyuan Yang et al.
The Plant cell, 32(5), 1749-1767 (2020-03-15)
In plants, changes in cell size and shape during development fundamentally depend on the ability to synthesize and modify cell wall polysaccharides. The main classes of cell wall polysaccharides produced by terrestrial plants are cellulose, hemicelluloses, and pectins. Members of
Mouhannad Malek et al.
Molecular cell, 68(3), 566-580 (2017-10-24)
The PI3K signaling pathway regulates cell growth and movement and is heavily mutated in cancer. Class I PI3Ks synthesize the lipid messenger PI(3,4,5)P3. PI(3,4,5)P3 can be dephosphorylated by 3- or 5-phosphatases, the latter producing PI(3,4)P2. The PTEN tumor suppressor is thought
Ulrike Bruning et al.
Cell metabolism, 28(6), 866-880 (2018-08-28)
The role of fatty acid synthesis in endothelial cells (ECs) remains incompletely characterized. We report that fatty acid synthase knockdown (FASNKD) in ECs impedes vessel sprouting by reducing proliferation. Endothelial loss of FASN impaired angiogenesis in vivo, while FASN blockade reduced
Alexander Fauland et al.
Journal of lipid research, 52(12), 2314-2322 (2011-10-01)
This work aims to combine chromatographic retention, high mass resolution and accuracy, MS/MS spectra, and a package for automated identification and quantitation of lipid species in one platform for lipidomic analysis. The instrumental setup elaborated comprises reversed-phase HPLC coupled to
Milena Vukotic et al.
Molecular cell, 67(3), 471-483 (2017-07-18)
Mutations in mitochondrial acylglycerol kinase (AGK) cause Sengers syndrome, which is characterized by cataracts, hypertrophic cardiomyopathy, and skeletal myopathy. AGK generates phosphatidic acid and lysophosphatidic acid, bioactive phospholipids involved in lipid signaling and the regulation of tumor progression. However, the

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