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Merck
CN

999991P

Avanti

18:0 Diether PC

1,2-di-O-octadecyl-sn-glycero-3-phosphocholine, powder

别名:

1,2-di-O-SPC

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About This Item

经验公式(希尔记法):
C44H92NO6P
CAS号:
分子量:
762.18
MDL编号:
UNSPSC代码:
51191904
NACRES:
NA.25

表单

powder

包装

pkg of 1 × 10 mg (999991P-10mg)
pkg of 1 × 500 mg (999991P-500mg)

制造商/商品名称

Avanti Research - A Croda Brand 999991P

脂质类型

cardiolipins
phospholipids

运输

dry ice

储存温度

−20°C

SMILES字符串

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCCCCCCCCCCCCCCCCC)COCCCCCCCCCCCCCCCCCC)=O

InChI key

HVVJCLFLKMGEIY-USYZEHPZSA-N

一般描述

18:0 Diether PC (phosphocholine) is a class of glycerophospholipids that has two octadecane chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It has choline as the alcohol moiety, attached to the phosphate group.

应用

18:0 Diether PC or 1,2-di-O-octadecyl-sn-glycero-3-phosphocholine might be used:
  • as a nonhydrolizable ether lipid in calcein-containing vesicles for calcein encapsulation
  • to prepare ether-linked phospholipid bilayer membrane for examining its thermotropic and barotropic phase transitions
  • as a component of internal standard mixture for lipid extraction from plasma sample using mass spectromety

包装

20 mL Clear Glass Screw Cap Vial (999991P-500mg)
5 mL Amber Glass Screw Cap Vial (999991P-10mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

法规信息

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Hitoshi Matsuki et al.
Biochimica et biophysica acta, 1768(3), 479-489 (2006-12-05)
The bilayer phase transitions of a series of ether-linked phospholipids, 1,2-dialkylphosphatidylcholines containing linear saturated alkyl chain (C(n)=12, 14, 16 and 18), were observed by differential scanning calorimetry (DSC) under ambient pressure and light-transmittance measurements under high pressure. The thermodynamic quantities
Chad Leidy et al.
Biophysical journal, 90(9), 3165-3175 (2006-02-08)
Secretory human phospholipase A2 type IIA (PLA2-IIA) catalyzes the hydrolysis of the sn-2 ester bond in glycerolipids to produce fatty acids and lysolipids. The enzyme is coupled to the inflammatory response, and its specificity toward anionic membrane interfaces suggests a
John M Dean et al.
Protein & cell, 9(2), 196-206 (2017-05-20)
Ether lipids, such as plasmalogens, are peroxisome-derived glycerophospholipids in which the hydrocarbon chain at the sn-1 position of the glycerol backbone is attached by an ether bond, as opposed to an ester bond in the more common diacyl phospholipids. This
Juergen Graessler et al.
PloS one, 4(7), e6261-e6261 (2009-07-16)
Dyslipoproteinemia, obesity and insulin resistance are integrative constituents of the metabolic syndrome and are major risk factors for hypertension. The objective of this study was to determine whether hypertension specifically affects the plasma lipidome independently and differently from the effects

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