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Merck
CN

999985P

Avanti

4ME 16:0 Diether PE

Avanti Polar Lipids 999985P, powder

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别名:
1,2-di-O-phytanyl-sn-glycero-3-phosphoethanolamine
经验公式(希尔记法):
C45H94NO6P
分子量:
776.20
UNSPSC代码:
12352211
NACRES:
NA.25

形式

powder

包装

pkg of 1 × 25 mg (999985P-25mg)
pkg of 1 × 5 mg (999985P-5mg)

制造商/商品名称

Avanti Polar Lipids 999985P

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OCC[NH3+])=O)(OCCC(C)CCCC(C)CCCC(C)CCCC(C)C)COCCC(C)CCCC(C)CCCC(C)CCCC(C)C

一般描述

4ME 16:0 Diether PE or 1,2-di-O-phytanyl-sn-glycero-3-phosphoethanolamine is a class of glycerophospholipids having two phytane chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It has ethanolamine as the alcohol moiety, attached to the phosphate group.

应用

4ME 16:0 Diether PE or 1,2-di-O-phytanyl-sn-glycero-3-phosphoethanolamine is suitable:
  • for nanoformulation of liposomal docosahexaenoic acid (DHA) and ghost (no DHA, control) liposomes
  • for the preparation of archaeal-like lipid bilayers to examine the effect of humidity and temperature on it
  • as an internal standard in tandem mass spectrometry/mass spectrometry/mass spectrometry (MS3) to study the effect on glycerophosphoethanolamine (GPEtn) species upon the exposure of human polymorphonuclear leukocytes to A23187 and granulocyte macrophage–colony-stimulating factor/formyl-methionyl-leucyl-phenylalanine stimuli
  • as an internal standard in lipid extraction using methyl-tert-butylether (MTBE)/methanol protocol

包装

5 mL Clear Glass Sealed Ampule (999985P-25mg)
5 mL Clear Glass Sealed Ampule (999985P-5mg)

WGK

WGK 3


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Marta Salvador-Castell et al.
International journal of molecular sciences, 21(5) (2020-03-12)
Archaea, the most extremophilic domain of life, contain ether and branched lipids which provide extraordinary bilayer properties. We determined the structural characteristics of diether archaeal-like phospholipids as functions of hydration and temperature by neutron diffraction. Hydration and temperature are both
Christine G Skibinski et al.
Chemico-biological interactions, 252, 1-8 (2016-04-05)
The risk of breast cancer can be influenced by certain dietary components, such as the amount and type of dietary fatty acids ingested. Docosahexaenoic acid (DHA), a component of fish oil, is known to suppress rat mammary carcinogenesis, reduce cell
Celine Fernandez et al.
PloS one, 8(8), e71846-e71846 (2013-08-24)
We tested whether characteristic changes of the plasma lipidome in individuals with comparable total lipids level associate with future cardiovascular disease (CVD) outcome and whether 23 validated gene variants associated with coronary artery disease (CAD) affect CVD associated lipid species.
Analysis of polyunsaturated aminophospholipid molecular species using isotope-tagged derivatives and tandem mass spectrometry/mass spectrometry/mass spectrometry
Berry KAZ and Murphy RC
Analytical Biochemistry, 349(1), 118-128 (2006)
Marta Salvador-Castell et al.
Biochimica et biophysica acta. Biomembranes, 1862(2), 183130-183130 (2019-11-18)
It is now well established that cell membranes are much more than a barrier that separate the cytoplasm from the outside world. Regarding membrane's lipids and their self-assembling, the system is highly complex, for example, the cell membrane needs to

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