产品名称
1-C16 Ether MG, Avanti Research™ - A Croda Brand 999971P, powder
SMILES string
[H][C@@](CO)(O)COCCCCCCCCCCCCCCCC
InChI
1S/C19H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-22-18-19(21)17-20/h19-21H,2-18H2,1H3
InChI key
OOWQBDFWEXAXPB-UHFFFAOYSA-N
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 250 mg (999971P-250mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 999971P
lipid type
phospholipids
neutral lipids
shipped in
dry ice
storage temp.
−20°C
Application
1-C16 Ether MG or 1-O-hexadecyl-sn-glycerol (HG) might be used to study its effect on target gene expression in HepG2 cells. It might also be used to promote plasmalogen biosynthesis in lymphoblasts derived from Barth syndrome (BTHS) patients.
Biochem/physiol Actions
1-C16 Ether MG or 1-O-hexadecyl-sn-glycerol (HG) acts as a precursor for plasma plasmalogen (PI) biosynthesis. It is essential for maintaining the plasmalogen levels in cell lines.
General description
1-C16 Ether MG or 1-O-hexadecyl-sn-glycerol (HG) is a neutral lipid containing a saturated 16-carbon alkyl chain ether and an uncharged headgroup.
Packaging
20 mL Clear Glass Screw Cap Vial (999971P-250mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Extrinsic effectors regulating genes for plasmalogen biosynthetic enzymes in HepG2 cells
Maeba R, et al.
Biomedical Research and Clinical Practice, 2 (2017)
Santosh Phuyal et al.
The Journal of biological chemistry, 290(7), 4225-4237 (2014-12-19)
Exosomes are vesicles released by cells after fusion of multivesicular bodies with the plasma membrane. In this study, we have investigated whether ether lipids affect the release of exosomes in PC-3 cells. To increase the cellular levels of ether lipids
Sara L Morales-Lázaro et al.
The Journal of biological chemistry, 289(35), 24079-24090 (2014-07-19)
The transient receptor potential vanilloid 1 (TRPV1) ion channel is a polymodal protein that responds to various stimuli, including capsaicin (the pungent compound found in chili peppers), extracellular acid, and basic intracellular pH, temperatures close to 42 °C, and several
José Carlos Bozelli et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1865(6), 158677-158677 (2020-03-04)
In Barth syndrome (BTHS) mutations in tafazzin leads to changes in both the quantities and the molecular species of cardiolipin (CL), which are the hallmarks of BTHS. Contrary to the well-established alterations in CL associated with BTHS; recently a marked
Akira Abe et al.
Journal of lipid research, 48(10), 2255-2263 (2007-07-14)
A novel lysosomal phospholipase A(2) (LPLA2) with specificity toward phosphatidylethanolamine and phosphatidylcholine was previously purified and cloned. LPLA2 transfers sn-1 or sn-2 acyl groups of phospholipids to the C1 hydroxyl of the short-chain ceramide N-acetylsphingosine (NAS) under acidic conditions. The
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