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Merck
CN

900100P

Avanti

PGE1

Avanti Polar Lipids 900100P, powder

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别名:
前列腺素E1
经验公式(希尔记法):
C20H34O5
CAS号:
分子量:
354.48
UNSPSC代码:
12352211
NACRES:
NA.25

形式

powder

包装

pkg of 1 × 1 mg (900100P-1mg)

制造商/商品名称

Avanti Polar Lipids 900100P

脂质类型

neutral glycerides
neutral lipids

运输

dry ice

储存温度

−20°C

SMILES字符串

O=C1[C@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)C1

InChI

1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1

InChI key

GMVPRGQOIOIIMI-DWKJAMRDSA-N

一般描述

前列腺素(PGs)属于类花生酸(eicosanoid)类生物化合物,是花生四烯酸代谢过程中形成的氧衍生物。PG位于哺乳动物的每一种组织和体液中。它首先在人类前列腺中被发现,因此得名前列腺素。

应用

前列腺素E1(PGE1)可用于研究其形成银加合物的能力。它也适用于趋化性测定。

生化/生理作用

前列腺素(PG)介导血管舒张和血管收缩,前列腺素E系列是一种高效的血管舒张剂。它有效地引起红斑。PGE1被认为是强效的致热因子(pyretic factor),并通过脑室起作用。它可用于在手术前延长患有导管依赖型先天性心脏病的新生儿的心血管功能。它可用作血管扩张剂。在精子中PGE1显示出孕激素诱导的Ca2 +瞬变。

包装

5 mL琥珀色玻璃螺旋盖小瓶(900100P-1mg)

象形图

Skull and crossbones

警示用语:

Danger

危险声明

预防措施声明

危险分类

Acute Tox. 3 Oral

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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The Prostaglandins (2013)
Ayanna U Jackson et al.
Analytical and bioanalytical chemistry, 399(1), 367-376 (2010-11-12)
Spray solvent doped with silver ions increases the ease of olefin detection by desorption electrospray ionization (DESI). Characteristic silver adducts were generated in up to 50 times greater abundance when compared to conventional DESI spray solvents for the biologically significant
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Steroid hormone progesterone released by cumulus cells surrounding the egg is a potent stimulator of human spermatozoa. It attracts spermatozoa towards the egg and helps them penetrate the egg's protective vestments. Progesterone induces Ca(2+) influx into spermatozoa and triggers multiple
Erminia Bentivegna et al.
Le infezioni in medicina, 23(1), 69-73 (2015-03-31)
Prostaglandins appear to reduce biofilm formation and chronicization of infections, and stimulate a rapid and effective clearance of infecting micro-organisms. We report a case of recovery from methicillin-susceptible Staphylococcus aureus (MSSA) osteomyelitis after multidisciplinary management with antibiotics, anti-thrombotics and prostaglandin
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Annual review of entomology, 51, 25-44 (2005-12-08)
Prostaglandins and other eicosanoids are oxygenated metabolites of certain polyunsaturated fatty acids. These compounds are well known for their important actions in mammalian physiology and disease. Recent work has revealed the presence and biological actions of eicosanoids in insects and

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