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Merck
CN

890900O

Avanti

ALC-0315

Avanti Research - A Croda Brand

别名:

ALC 0315, 6-((2-hexyldecanoyl)oxy)-N-(6-((2-hexyldecanoyl)oxy)hexyl)-N-(4-hydroxybutyl)hexan-1-aminium

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About This Item

经验公式(希尔记法):
C48H95NO5
分子量:
766.27
UNSPSC代码:
12352211
NACRES:
NA.25

形式

oil

包装

pkg of 1x1 g (890900O-1G)
pkg of 1x100 mg (890900O-100MG)
pkg of 1x200 mg (890900O-200MG)
pkg of 1x25 mg (890900O-25MG)
pkg of 1x50 mg (890900O-50MG)
pkg of 1x500 mg (890900O-500MG)

制造商/商品名称

Avanti Research - A Croda Brand

技术

thin layer chromatography (TLC): suitable

应用

advanced drug delivery

脂质类型

cationic lipids

运输

dry ice

储存温度

−20°C

SMILES字符串

O=C(C(CCCCCC)CCCCCCCC)OCCCCCCN(CCCCO)CCCCCCOC(C(CCCCCCCC)CCCCCC)=O

应用


  • Cationic Lipid Pairs Enhance Liver-to-Lung Tropism of Lipid Nanoparticles for In Vivo mRNA Delivery.: ALC-0315 plays a critical role in this study, enhancing the delivery efficiency of mRNA therapies from liver to lung. This research could lead to improved treatment options for various pulmonary diseases (Zeng et al., 2024).

  • Engineering LNPs with polysarcosine lipids for mRNA delivery.: Demonstrates ALC-0315′s application in designing lipid nanoparticles that efficiently deliver mRNA, showcasing potential advancements in gene therapy (Kang et al., 2024).

  • Tumor-activated IL-2 mRNA delivered by lipid nanoparticles for cancer immunotherapy.: Utilizes ALC-0315 in the development of lipid nanoparticles that activate under tumor-specific conditions to deliver immunotherapeutic agents, offering a targeted approach to cancer treatment (Jiang et al., 2024).

包装

  • 5 mL Amber Glass Screw Cap Vial (890900O-25MG)
  • 5 mL Amber Glass Screw Cap Vial (890900O-50MG)
  • 5 mL Amber Glass Screw Cap Vial (890900O-100MG)
  • 5 mL Amber Glass Screw Cap Vial (890900O-200MG)
  • 5 mL Amber Glass Screw Cap Vial (890900O-500MG)
  • 30 mL Amber Glass Screw Cap Vial(890900O-1G)

其他说明

Quantities limited to 50G in a calendar year per customer.

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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