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经验公式（希尔记法）:
C43H83NO8S
化学文摘社编号:
分子量:
774.19
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
18:1 TAP（DOTAP，MS盐）, Avanti Research™ - A Croda Brand 890895P, powder
SMILES string
[H]C(C[N+](C)(C)C)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.O=S([O-])(OC)=O
InChI
1S/C42H80NO4.CH4O4S/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-41(44)46-39-40(38-43(3,4)5)47-42(45)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;1-5-6(2,3)4/h20-23,40H,6-19,24-39H2,1-5H3;1H3,(H,2,3,4)/q+1;/p-1/b22-20-,23-21-;
InChI key
RSMRWWHFJMENJH-LQDDAWAPSA-M
assay
>99% (TLC)
form
powder
packaging
pkg of 2 × 100 mg (890895P-200mg)
pkg of 1 × 25 mg (890895P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 890895P
lipid type
cationic lipids
transfection
shipped in
dry ice
storage temp.
−20°C
Biochem/physiol Actions
1,2-二油酰基-3-三甲基铵-丙烷（DOTAP）为阳离子脂质，用于体内和体外核酸和蛋白递送。脂质组成和细胞类型会影响 DOTAP 的转染潜能。DOTAP介导造血干细胞(HSCs)的基因敲低技术。
Packaging
5 mL透明玻璃密封安瓿（890895P-200mg）
5 mL透明玻璃密封安瓿（890895P-25mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Sabata Martino et al.
Journal of biomedicine & biotechnology, 2009, 410260-410260 (2009-06-09)
RNA interference technology is an ideal strategy to elucidate the mechanisms associated with human CD34(+) hematopoietic stem cell differentiation into dendritic cells. Simple manipulations in vitro can unequivocally yield alloreactive or tolerogenic populations, suggesting key implications of biochemical players that
Dmitri Simberg et al.
Critical reviews in therapeutic drug carrier systems, 21(4), 257-317 (2005-01-11)
Cationic lipid-mediated nucleic acid and protein delivery is becoming increasingly popular for in vitro and in vivo applications. While the chemistry of cationic lipid carriers is moving very rapidly, and more and more sophisticated molecules are being developed, it is
Bieong-Kil Kim et al.
Biochimica et biophysica acta, 1848(10 Pt A), 1996-2001 (2015-06-27)
The effects of lipid compositions on their physicochemical properties and transfection efficiencies were investigated. Four liposome formulations with different 1,2-dioleoyl-3-trimethylammoniumpropane (DOTAP) to dioleoylphosphatidylethanolamine (DOPE) weight ratios were investigated, that is, weight ratios 1:0 (T1P0), 3:1 (T3P1), 1:1 (T1P1), and 1:3
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