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安全信息

890895C

Avanti

18:1 TAP (DOTAP, MS Salt)

Avanti Research™ - A Croda Brand 890895C

别名:

1,2-dioleoyl-3-trimethylammonium-propane (methyl sulfate salt)

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About This Item

经验公式（希尔记法）:
C43H83NO8S
CAS号:
144189-73-1
分子量:
774.19
UNSPSC代码:
12352211
NACRES:
NA.25

形式

liquid

包装

pkg of 1 × 2.5 mL (890895C-25mg)
pkg of 2 × 4 mL (890895C-200mg)

制造商/商品名称

Avanti Research™ - A Croda Brand 890895C

浓度

10 mg/mL (890895C-25mg)
25 mg/mL (890895C-200mg)

脂质类型

cationic lipids
transfection

运输

dry ice

储存温度

−20°C

SMILES字符串

[H]C(C[N+](C)(C)C)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.O=S([O-])(OC)=O

InChI

1S/C42H80NO4.CH4O4S/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-41(44)46-39-40(38-43(3,4)5)47-42(45)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;1-5-6(2,3)4/h20-23,40H,6-19,24-39H2,1-5H3;1H3,(H,2,3,4)/q+1;/p-1/b22-20-,23-21-;

InChI key

RSMRWWHFJMENJH-LQDDAWAPSA-M

相关类别

生化/生理作用

DOTAP (1,2-dioleoyl-3-trimethylammonium-propane) is a cationic lipid, used for in vitro and in vivo nucleic acid and protein delivery. The lipid composition and cell type affects the transfection potential of DOTAP. DOTAP mediates gene knockdown technique in hematopoietic stem cells (HSCs).

包装

5 mL Clear Glass Sealed Ampule (890895C-200mg)
5 mL Clear Glass Sealed Ampule (890895C-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

靶器官

Liver,Kidney, Respiratory system

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

does not flash

闪点(°C)

does not flash

法规信息

易制毒化学品（2类）
危险化学品

分析证书(COA)

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访问文档库

Efficient siRNA delivery by the cationic liposome DOTAP in human hematopoietic stem cells differentiating into dendritic cells
Martino S, et al.
BioMed Research International, 2009 (2009)
DOTAP (and other cationic lipids): chemistry, biophysics, and transfection
Simberg D, et al.
Critical Reviews in Therapeutic Drug Carrier Systems, 21(4) (2004)
DOTAP/DOPE ratio and cell type determine transfection efficiency with DOTAP-liposomes
Kim BK, et al.
Biochimica et Biophysica Acta - Biomembranes, 1848(10), 1996-2001 (2015)

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