形式
powder
包装
pkg of 1 × 200 mg (890880P-200mg)
pkg of 1 × 25 mg (890880P-25mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 890880P
脂质类型
cationic lipids
transfection
运输
dry ice
储存温度
−20°C
SMILES字符串
[H]C(C[N+](C)(C)C)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Cl-]
应用
1,2-硬脂酰-3-三甲基铵-丙烷（18:0 TAP）可用于：
- 通过薄膜水合技术制备三负载胆汁糖体（Tri-BLs）
- 配制脂质纳米颗粒（LNP），以测试其将 mRNA 包装成 LNP 的效率
- 制造单层空脂质体
- 制备脂质复合物
生化/生理作用
1,2-硬脂酰-3-三甲基铵-丙烷（18:0 TAP）是一种用于 DNA 转染的阳离子脂质。
包装
5 mL棕色玻璃螺旋盖小瓶（890880P-200mg）
5 mL棕色玻璃螺旋盖小瓶（890880P-25mg）
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
Hailing Yang et al.
Drug delivery, 26(1), 820-830 (2019-08-08)
Arthritis treatment has been challenging because of low drug exposure to the articular cavity. This study was intended to develop hyaluronic acid (HA)-functionalized bilosomes for targeted delivery of tripterine (Tri), an antiphlogistic phytomedicine, to the inflamed joint via ligand-receptor interaction.
Zhiqiang Sun et al.
Biomacromolecules, 13(10), 3395-3400 (2012-09-20)
Lipid-coated DNA nanoparticles (lipoplexes) are a powerful gene delivery tool with promising therapeutic applications. The mechanism of lipoplex assembly remains poorly understood. We explored DNA packing by a cationic lipid DSTAP (distearoyl trimethylammonium-propane) using magnetic tweezers. DSTAP-induced DNA condensation occurred
Maria Jose York-Duran et al.
Biomaterials science, 7(11), 4813-4826 (2019-09-20)
While ROS display crucial functions in many physiological processes, elevated ROS levels are also related to the initiation and progression of many severe diseases such as cancer, cardiovascular conditions or neurologic disorders. Research approaches to diminish ROS levels during disease
Siddharth Patel et al.
Journal of controlled release : official journal of the Controlled Release Society, 303, 91-100 (2019-04-16)
Retinal gene therapy has had unprecedented success in generating treatments that can halt vision loss. However, immunogenic response and long-term toxicity with the use of viral vectors remain a concern. Non-viral vectors are relatively non-immunogenic, scalable platforms that have had
Yuki Takechi-Haraya et al.
Langmuir : the ACS journal of surfaces and colloids, 34(26), 7805-7812 (2018-06-06)
It has recently been recognized that the mechanical properties of lipid nanoparticles play an important role during in vitro and in vivo behaviors such as cellular uptake, blood circulation, and biodistribution. However, there have been no quantitative investigations of the
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