推荐产品
形式
liquid
包装
pkg of 1 × 2.5 mL (890820C-25mg)
制造商/商品名称
Avanti Polar Lipids 890820C
浓度
10 mg/mL (890820C-25mg)
脂质类型
transfection
cationic lipids
运输
dry ice
储存温度
−20°C
SMILES字符串
[H]C(CN(C)C)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O
应用
1,2-distearoyl-3-dimethylammonium-propane (18:0 DAP) might be used to formulate lipid nanoparticles (LNPs) and to test its efficiency of packaging mRNA into an LNP. It might also be used in the preparation of “bubble liposomes” (BLs).
生化/生理作用
1,2-distearoyl-3-dimethylammonium-propane (18:0 DAP) is a cationic lipid and serves as a pH-sensitive transfection reagent.
包装
5 mL Clear Glass Sealed Ampule (890820C-25mg)
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
靶器官
Central nervous system
WGK
WGK 3
法规信息
易制毒化学品（2类）
危险化学品
Yoko Endo-Takahashi et al.
Biomaterials, 34(11), 2807-2813 (2013-01-25)
We have developed polyethyleneglycol (PEG)-modified liposomes (Bubble liposomes; BLs) that entrap ultrasound (US) contrast gas, and we have reported that the combination of BLs and US exposure was an effective tool for delivering pDNA and siRNA in vitro and in
Siddharth Patel et al.
Journal of controlled release : official journal of the Controlled Release Society, 303, 91-100 (2019-04-16)
Retinal gene therapy has had unprecedented success in generating treatments that can halt vision loss. However, immunogenic response and long-term toxicity with the use of viral vectors remain a concern. Non-viral vectors are relatively non-immunogenic, scalable platforms that have had
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