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经验公式（希尔记法）:
C39H73F3NO11PS
化学文摘社编号:
分子量:
852.03
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
14:1 EPC (Tf Salt), Avanti Research™ - A Croda Brand 890717O
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 10 mg (890717O-10mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 890717O
lipid type
transfection
cationic lipids
shipped in
dry ice
storage temp.
−20°C
Biochem/physiol Actions
1,2-dimyristoleoyl-sn-glycero-3-ethylphosphocholine (14:1 EPC) is less toxic and is biodegradable. It is known to possess efficient DNA transfection activity. 14:1 EPC is very closely identical to the natural triacylglyceride lipids.
General description
Ethylphosphocholine (EPC) are amphiphilic cationic lipids containing hydrophilic headgroup and lipophilic tail.
Packaging
5 mL Clear Glass Sealed Ampule (890717O-10mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
10 - Combustible liquids
wgk
WGK 3
Differentially charged hollow core/shell lipid-polymer-lipid hybrid nanoparticles for small interfering RNA delivery.
Jinjun Shi et al.
Angewandte Chemie (International ed. in English), 50(31), 7027-7031 (2011-06-24)
Mikhail A Galkin et al.
Journal of visualized experiments : JoVE, (134) (2018-04-24)
Detergents are indispensable for delivery of membrane proteins into 30-100 nm small unilamellar vesicles, while more complex, larger model lipid bilayers are less compatible with detergents. Here we describe a strategy for bypassing this fundamental limitation using fusogenic oppositely charged
Rumiana Koynova et al.
The journal of physical chemistry. B, 111(27), 7786-7795 (2007-06-19)
Some mixtures of two cationic lipids including phospholipid compounds (O-ethylphosphatidylcholines) as well as common, commercially available cationic lipids, such as dimethylammonium bromides and trimethylammonium propanes, deliver therapeutic DNA considerably more efficiently than do the separate molecules. In an effort to
Boris G Tenchov et al.
Biochimica et biophysica acta, 1778(10), 2405-2412 (2008-08-30)
Synthetic cationic lipids can be used as DNA carriers and are regarded to be the most promising non-viral gene carriers. For this investigation, six novel phosphatidylcholine (PC) cationic derivatives with various hydrophobic moieties were synthesized and their transfection efficiencies for
Rumiana Koynova et al.
Molecular pharmaceutics, 6(3), 951-958 (2009-04-04)
Synthetic cationic lipids are widely used components of nonviral gene carriers, and the factors regulating their transfection efficiency are the subject of considerable interest. In view of the important role that electrostatic interactions with the polyanionic nucleic acids play in
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