产品名称
14:0 EPC (Cl Salt), Avanti Research™ - A Croda Brand 890701C
SMILES string
O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O)OCC.[Cl-]
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (890701C-10mg), pkg of 1 × 2.5 mL (890701C-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 890701C
concentration
10 mg/mL (890701C-10mg), 10 mg/mL (890701C-25mg)
lipid type
transfection
cationic lipids
shipped in
dry ice
storage temp.
−20°C
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Application
14:0 EPC (Cl Salt) is suitable:
- for combining with a co-lipid, in liposome preparation by sonication
- for the preparation of cationic lipid mixtures to establish its superior transfection activity
- for the study of dehydration dynamics
Biochem/physiol Actions
14:0 EPC (Cl Salt) is a cationic lipid. It efficiently mediates gene delivery into the cells. 14:0 EPC (Cl Salt) serves as a non-viral delivery vector.
Packaging
5 mL Clear Glass Sealed Ampule (890701C-10mg)
5 mL Clear Glass Sealed Ampule (890701C-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
危险化学品
易制毒化学品（2类）
此项目有
Efficient in vivo delivery of DNA to pulmonary cells using the novel lipid EDMPC
Gorman CM
Gene Therapy, 4(9), 983-983 (1997)
Aspects of nonviral gene therapy: correlation of molecular parameters with lipoplex structure and transfection efficacy in pyridinium-based cationic lipids
Parvizi P, et al.
International Journal of Pharmaceutics, 461(1-2), 145-156 (2014)
Analysis of lipoplex structure and lipid phase changes
Liposomes, 399-423 (2010)
The dehydration dynamics of a model cell membrane induced by cholesterol analogue 6-ketocholestanol investigated using sum frequency generation vibrational spectroscopy
Ma S, et al.
Science China: Chemistry, 58(7), 1176-1186 (2015)
Rumiana Koynova et al.
The journal of physical chemistry. B, 111(27), 7786-7795 (2007-06-19)
Some mixtures of two cationic lipids including phospholipid compounds (O-ethylphosphatidylcholines) as well as common, commercially available cationic lipids, such as dimethylammonium bromides and trimethylammonium propanes, deliver therapeutic DNA considerably more efficiently than do the separate molecules. In an effort to
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