产品名称
14:0 PEG1000 PE, Avanti Research™ - A Croda Brand 880710P, powder
InChI key
JEVVDLLTQSGDHA-WDFSKNPFSA-N
SMILES string
[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[NH4+]
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 25 mg (880710P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 880710P
shipped in
dry ice
storage temp.
−20°C
Application
14:0 PEG1000 PE or 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] is suitable for use in lipid aggregates to characterize and study its use as a coating and a carrier in capillary electrophoresis. It might be used to prepare sterically stabilized liposome and study its characteristics by small-angle X-ray scattering (SAXS) method.
Biochem/physiol Actions
Stabilized lipid aggregates formed using 14:0 PEG1000 PE or 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] serve as model membranes in biotechnical and pharmaceutical applications. Polyethylene glycol (PEGs) of molecular mass less than or equal to 5000 are preferred for vesicle coating, serving for efficient delivery of the drug. PEG conjugated lipids improve liposome packing in the water/hydrocarbon interface.
Packaging
5 mL Amber Glass Screw Cap Vial (880710P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids
wgk
WGK 3
Maria V Lindén et al.
Electrophoresis, 29(4), 852-862 (2008-01-24)
PEG-stabilized lipid aggregates are a promising new class of model membranes in biotechnical and pharmaceutical applications. CE techniques, field-flow fractionation, light scattering, quartz crystal microbalance (QCM), and microscopic techniques were used to study aggregates composed of 1-palmitoyl-2-oleyl-sn-glycero-phosphatidylcholine (POPC) and PEG-lipid
Z Varga et al.
Chemistry and physics of lipids, 165(4), 387-392 (2012-01-10)
Synchrotron small-angle X-ray scattering analysis of the bilayer structure of a pharmacologically relevant sterically stabilized liposome system is presented. Describing the electron density profile of the bilayer with the superposition of Gaussian functions, the contribution of the poly(ethylene glycol) (PEG)
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