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安全信息

880620P

Avanti

18:0 PEG750 PE

Avanti Research™ - A Croda Brand 880620P, powder

别名:

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-750] (ammonium salt)

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About This Item

CAS号:
474922-77-5
UNSPSC代码:
12352211
NACRES:
NA.25

表单

powder

包装

pkg of 1 × 200 mg (880620P-200mg)
pkg of 1 × 25 mg (880620P-25mg)

制造商/商品名称

Avanti Research™ - A Croda Brand 880620P

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+]

InChI key

QAVSYMFTABOITA-CQZUBJGASA-N

相关类别

一般描述

18:0 PEG750 PE is a polyethylene glycol (PEG) conjugated phospholipid. The molecular weight and exact mass are averages based on the polydispersity of PEG.

应用

18:0 PEG750 PE might be used to PEGylate lipoplexes and to study the feasibility of its entrapment into a solid matrix system for prolonged delivery of siRNA in vaginal mucus.

生化/生理作用

18:0 PEG750 PE is useful as a micelle-forming component.

包装

20 mL Clear Glass Screw Cap Vial (880620P-200mg)
5 mL Clear Glass Sealed Ampule (880620P-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 3

法规信息

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历史批次信息供参考:

分析证书(COA)

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Rupa R Sawant et al.
International journal of pharmaceutics, 374(1-2), 114-118 (2009-05-19)
Cell-penetrating peptide (TATp) was attached to the distal tips of polyethyleneglycol (PEG) moieties of polyethyleneglycol-phosphatidylethanolamine (PEG-PE) micelles loaded with paclitaxel (PCT). The TATp-modified micelles demonstrated an increased interaction with cancer cells compared to non-modified micelles resulting in a significant increase
Tania Furst et al.
Journal of controlled release : official journal of the Controlled Release Society, 236, 68-78 (2016-06-23)
Topical vaginal sustained delivery of siRNA presents a significant challenge due to the short residence time of formulations. Therefore, a drug delivery system capable to adhere to the vaginal mucosa is desirable, as it could allow a prolonged delivery and

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