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Merck
CN

880530C

Avanti

18:1 PEG550 PE

Avanti Polar Lipids 880530C

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别名:
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] (ammonium salt)
UNSPSC代码:
12352211
NACRES:
NA.25

形式

liquid

包装

pkg of 1 × 2.5 mL (880530C-25mg)

制造商/商品名称

Avanti Polar Lipids 880530C

浓度

10 mg/mL (880530C-25mg)

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]

一般描述

18:1 PEG550 PE is a polyethylene glycol (PEG) conjugated phospholipid. PEGylated phospholipids are amphiphilic polymers, The molecular weight and exact mass are averages based on the polydispersity of PEG.

应用

18:1 PEG550 PE is suitable for liposome formation.

生化/生理作用

The use of 18:1 PEG550 PE in liposomes reduces the random binding of quantum dot tagged proteins to the lipid bilayer. Polyethylene glycol (PEG) conjugated phospholipids are known to protect the steric nature of liposomes. Hence, they are commonly recommended for use in liposome formulation. PEGylated lipids are used as drug carriers. Use of highly concentrated PEG-lipids makes the possibility of mixed micelles.

包装

5 mL Clear Glass Sealed Ampule (880530C-25mg)

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system

WGK

WGK 3

法规信息

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Micro- and Nanoengineering of the Cell Surface (2014)
Teresa Fazio et al.
Langmuir : the ACS journal of surfaces and colloids, 24(18), 10524-10531 (2008-08-08)
Single molecule visualization of protein-DNA complexes can reveal details of reaction mechanisms and macromolecular dynamics inaccessible to traditional biochemical assays. However, these techniques are often limited by the inherent difficulty of collecting statistically relevant information from experiments explicitly designed to
Kenneth K Y Ho et al.
PloS one, 12(3), e0174689-e0174689 (2017-03-31)
Development of artificial cell models requires encapsulation of biomolecules within membrane-bound compartments. There have been limited studies of using mammalian cell-free expression (CFE) system as the 'cytosol' of artificial cells. We exploit glass capillary droplet microfluidics for the encapsulation of
Sirkku Hanski et al.
Biomacromolecules, 11(12), 3440-3447 (2010-10-27)
We report on highly ordered oblique self-assemblies in ionic complexes of PEGylated triple-tail lipids and cationic polypeptides, as directed by side-chain crystallization, demonstrating also reversible oblique-to-hexagonal order-order transitions upon melting of the side chains. This is achieved in bulk by
Maria C Sandström et al.
Langmuir : the ACS journal of surfaces and colloids, 23(8), 4192-4198 (2007-03-09)
Polyethylene glycol (PEG)-conjugated lipids are commonly employed for steric stabilization of liposomes. When added in high concentrations PEG-lipids induce formation of mixed micelles, and depending on the lipid composition of the sample, these may adapt either a discoidal or a

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