形式
powder
包装
pkg of 2 × 100 mg (880230P-200mg)
pkg of 1 × 25 mg (880230P-25mg)
制造商/商品名称
Avanti Research™ - A Croda Brand 880230P
运输
dry ice
储存温度
−20°C
SMILES字符串
[H][C@@](COP([O-])(OCCNC([(OCH2CH2)113OCH3])=O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]
应用
18:1 PEG5000 PE或1,2-二油酰基-sn-甘油-3-磷酸乙醇胺-N-[甲氧基(聚乙二醇)-5000可用于脂质双层制备,以及DOX游离碱负载的混合树枝状聚合物胶束(MDM)制备,用于肿瘤靶向递送siRNA和药物。
生化/生理作用
18:1 PEG5000 PE,也称为1,2-二油酰基-sn-甘油-3-磷酸乙醇胺-N-[甲氧基(聚乙二醇)-5000](PEG5k-DOPE)与脂质修饰的树枝状聚合物共聚物结合使用,可将siRNA和药物共同递送至肿瘤。
包装
5 mL透明玻璃密封安瓿(880230P-200mg)
5 mL透明玻璃密封安瓿(880230P-25mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
No data available
闪点(°C)
No data available
TCR--pMHC bond conformation controls TCR ligand discrimination
Cellular & Molecular Immunology (2019)
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 136, 18-28 (2019-01-12)
Multidrug resistance (MDR) significantly decreases the therapeutic efficiency of anti-cancer drugs. Its reversal could serve as a potential method to restore the chemotherapeutic efficiency. Downregulation of MDR-related proteins with a small interfering RNA (siRNA) is a promising way to reverse
Cellular & molecular immunology, 17(3), 203-217 (2019-09-19)
A major unanswered question is how a TCR discriminates between foreign and self-peptides presented on the APC surface. Here, we used in situ fluorescence resonance energy transfer (FRET) to measure the distances of single TCR-pMHC bonds and the conformations of
The Journal of cell biology, 219(6) (2020-05-22)
Blockade antibodies of the immunoinhibitory receptor PD-1 can stimulate the anti-tumor activity of T cells, but clinical benefit is limited to a fraction of patients. Evidence suggests that BTLA, a receptor structurally related to PD-1, may contribute to resistance to
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