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Merck
CN

880230P

Avanti

18:1 PEG5000 PE

Avanti Research - A Croda Brand 880230P, powder

别名:

1,2-二油酰基-sn-甘油-3-磷酸乙醇胺-N-[甲氧基(聚乙二醇)-5000](铵盐)

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About This Item

UNSPSC代码:
12352211
NACRES:
NA.25

形式

powder

包装

pkg of 2 × 100 mg (880230P-200mg)
pkg of 1 × 25 mg (880230P-25mg)

制造商/商品名称

Avanti Research - A Croda Brand 880230P

运输

dry ice

储存温度

−20°C

SMILES字符串

[H][C@@](COP([O-])(OCCNC([(OCH2CH2)113OCH3])=O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]

应用

18:1 PEG5000 PE或1,2-二油酰基-sn-甘油-3-磷酸乙醇胺-N-[甲氧基(聚乙二醇)-5000可用于脂质双层制备,以及DOX游离碱负载的混合树枝状聚合物胶束(MDM)制备,用于肿瘤靶向递送siRNA和药物。

生化/生理作用

18:1 PEG5000 PE,也称为1,2-二油酰基-sn-甘油-3-磷酸乙醇胺-N-[甲氧基(聚乙二醇)-5000](PEG5k-DOPE)与脂质修饰的树枝状聚合物共聚物结合使用,可将siRNA和药物共同递送至肿瘤。

包装

5 mL透明玻璃密封安瓿(880230P-200mg)
5 mL透明玻璃密封安瓿(880230P-25mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

No data available

闪点(°C)

No data available


分析证书(COA)

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TCR--pMHC bond conformation controls TCR ligand discrimination
Sasmal DK, et al.
Cellular & Molecular Immunology (2019)
Jiayi Pan et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 136, 18-28 (2019-01-12)
Multidrug resistance (MDR) significantly decreases the therapeutic efficiency of anti-cancer drugs. Its reversal could serve as a potential method to restore the chemotherapeutic efficiency. Downregulation of MDR-related proteins with a small interfering RNA (siRNA) is a promising way to reverse
Dibyendu K Sasmal et al.
Cellular & molecular immunology, 17(3), 203-217 (2019-09-19)
A major unanswered question is how a TCR discriminates between foreign and self-peptides presented on the APC surface. Here, we used in situ fluorescence resonance energy transfer (FRET) to measure the distances of single TCR-pMHC bonds and the conformations of
Xiaozheng Xu et al.
The Journal of cell biology, 219(6) (2020-05-22)
Blockade antibodies of the immunoinhibitory receptor PD-1 can stimulate the anti-tumor activity of T cells, but clinical benefit is limited to a fraction of patients. Evidence suggests that BTLA, a receptor structurally related to PD-1, may contribute to resistance to

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